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EP0264889A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Glycolipid containing N-glycolylneuraminic acid and method of procuding the same

Assignee: Mect Corp
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Filing: 1987-10-19
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Granted: —
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Expires: 2007-10-19
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Abstract

Abstract The present invention provides ganglioside-related compounds expressed by the following formula: (wherein R 1 denotes a hydrogen atom or SiR 3 R 4 R 5 (wherein R 3 and R 4 each denotes a methyl or phenyl group, and R 5 denotes a tertiary butyl or dimethylphenylmethyl group), and R 2 denotes a hydrogen atom, a trityl group, or (wherein M denotes an alkali metal atom)) and methods of producing the same. These ganglioside-related compounds are useful as markers for the early detection of cancer and in the immunotherapy for cancer.

Inventors

  • 👤 Tomoya Ogawa
  • 👤 Masaaki Numata
  • 👤 Mamoru Sugimoto
  • 👤 Shohei Shibayama
  • 👤 Shoji Yoshimura
  • 👤 Masayoshi Ito
  • 👤 Yoshiyasu Shitori

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-06 05:17
CPC Classifications
C; C07; C07H; C07H13/00; C07H13/02; C07H13/04; C07H13/06; C07H15/00; C07H15/02; C07H15/04; C07H15/10

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 62 words
(1) Ganglioside-related compounds expressed by the following formula: (wherein R 1 denotes a hydrogen atom or SiR 3 R 4 R 5 (wherein R 3 and Rt each denotes a methyl or phenyl group, and R 5 denotes a tertiary butyl or dimethylphenylmethyl group), and R 2 denotes a hydrogen atom, a trityl group, or (wherein M denotes an alkali metal atom)).
Claim 2
Dependent Claim 42 words
(2) A method of producing ganglioside-related compounds characterized by hydrolyzing compounds expressed by the following formula: (wherein T = OCOCH 3 and Ac = COCH 3 ) to produce compounds expressed by the following formula: (wherein M denotes an alkali metal atom).
Claim 3
Dependent Claim 50 words
(3) A method of producing ganglioside-related compounds characterized by acetylating compounds expressed by the following formula: (wherein Si'BuPh 2 denotes a diphenyl-t-butylsilyl group) to obtain compounds expressed by the following formula: which are then hydrolyzed to obtain compounds expressed by the following formula: (wher.ein M denotes an alkali metal atom).

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