EP0248447A2
Expired / Lapsed
EP
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Sustained release formulations
Assignee: Warner Lambert Co LLC
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Filing: 1987-06-05
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Granted: —
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Expires: 2007-06-05
Abstract
Abstract Drug delivery systems which exhibit sustained release properties when administered are produced using a "dual control" system which employs polymeric agents in core and membrane portions.
Inventors
- 👤 Reginald Phillips
- 👤 Krishnayya Bikkina
- 👤 Sadath U. Kahn
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-26 14:12
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/28; A61K9/2886; A61K9/2004; A61K9/2022; A61K9/205; A61K9/2054; A61K9/2806; A61K9/2833; A61K9/284; A61K9/2846; A61K9/286; A61K9/2866
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
42 words
A delivery system for sustained release dosage forms which comprises: (1) a core portion which contains a beneficial agent and a gelling polymer, and (2) a semipermeable membrane around the core which contains (a) a cellulosic polymer and (b) an acrylic polymer.
Claim 2
Dependent Claim
42 words
A delivery system for sustained release dosage forms which comprises: (1) a core portion which contains a beneficial agent and a gelling polymer, and (2) a semipermeable membrane around the core which contains (a) a cellulosic polymer and (b) an acrylic polymer.
Claim 3
Dependent Claim
29 words
The delivery system of claim 1 wherein the core portion contains about 12 to about 30 wt. % polymer and about 10 to about 15 wt. % beneficial agent.
Claim 4
Dependent Claim
17 words
The delivery system of claim 2 whenever the core contains hydroxyethyl cellulose and at least one drug.
Claim 5
Dependent Claim
12 words
The delivery system of claim 3 wherein the drug is procainamide hydrochloride.
Claim 6
Dependent Claim
56 words
A process for producing solid dosage forms which exhibit sustained release properties when administered which comprises the steps of: (1) producing a solid core containing at least one drug and at least one gelling polymer, and (2) coating the core of step (1) with at least one semipermeable coating which contains cellulosic and acrylic polymer components.
Claim 7
Dependent Claim
56 words
A process for producing solid dosage forms which exhibit sustained release properties when administered which comprises the steps of: (1) producing a solid core containing at least one drug and at least one gelling polymer, and (2) coating the core of step (1) with at least one semipermeable coating which contains cellulosic and acrylic polymer components.
Claim 8
Dependent Claim
14 words
T he process of claim 5 wherein the gelling polymer comprises hydroxy ethyl cellulose.
Claim 9
Dependent Claim
37 words
The process of claim 5 wherein there is added the steps of: (3) coating the product of step (2) with a polymeric color coat, and (4) coating the product of step (3) with a polymeric clear coat.
Claim 10
Dependent Claim
12 words
The process of Claim 7 wherein the gelling polymer comprises hydroxyethyl cellulose.
Claim 11
Dependent Claim
13 words
The process of Claims 5 to 8, wherein the drug is procainamide hydrochloride.
Claim 12
Dependent Claim
28 words
The process of Claims 5 to 9, wherein the core portion contains about 12 to about 30 wt.% polymer and about 10 to about 15 wt.% beneficial agent.
References Cited (Backward Citations)
No citation records indexed.
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