EP0230247A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Adsorbent for removing complement component
Assignee: Kanegafuchi Chemical Industry Co Ltd
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Filing: 1987-01-13
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Granted: —
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Expires: 2007-01-13
Abstract
Abstract An adsorbent for removing a complement component and/or an activated complement component, which comprises a water-insoluble porous gel having an anionic functional group at least on a part of the surface of said gel. The adsorbent can remove the complement component and the activated complement component efficiently and selectively from body fluid. Also, the activation of the complement system caused by contacting with the absorbent is not observed. Accordingly, the adsorbent of the invention is useful for removing the complement component and/or the activated complement component from body fluid in extracorporeal circulation treatment.
Inventors
- 👤 Nobutaka Tani
- 👤 Tsuneo Hayashi
- 👤 Shigeo Furuyoshi
- 👤 Youko Nagano
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-09 05:43
CPC Classifications
B; B01; B01J; B01J20/00; B01J20/22; B01J20/26; A; A61; A61M; A61M1/00; A61M1/36; A61M1/3679; B01J20/30; B01J20/32; B01J20/3202; B01J20/3204; B01J20/3206; B01J20/3208; B01J20/321; B01J20/3212; B01J20/3214; B01J20/3217; B01J20/3219; B01J20/3231; B01J20/3242; B01J20/3244; B01J20/3246; B01J20/3248; B01J20/3251; B01J20/3257; B01J20/3268; B01J20/327; B01J20/3272; B01J20/3274; B01J20/3276; B01J20/328; B01J20/3282
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
34 words
An adsorbent for removing a complement component and/or an activated complement component, which comprises a water-insoluble porous gel having an anionic functional group at least on a part of the surface of said gel.
Claim 2
Dependent Claim
34 words
An adsorbent for removing a complement component and/or an activated complement component, which comprises a water-insoluble porous gel having an anionic functional group at least on a part of the surface of said gel.
Claim 3
Dependent Claim
13 words
The adsorbent of Claim l, wherein said gel comprises a hydroxyl group-containing compound.
Claim 4
Dependent Claim
29 words
The adsorbent of Claim l, wherein said anionic functional group is at least one group selected from the group consisting of carboxyl group, sulfonic acid group and sulfate group.
Claim 5
Dependent Claim
19 words
The adsorbent of Claim l, wherein an anionic functional group-containing compound is immobilized on said gel with covalent bond.
Claim 6
Dependent Claim
27 words
The adsorbent of Claim l, which has an exclusion limit suitable for removing the complement component within the range of 2 × l0⁵ to 5 × l0⁷.
Claim 7
Dependent Claim
28 words
The adsorbent of Claim l, which has an exclusion limit suitable for removing the activated complement component within the range of l × l0⁴ to l × l0⁶.
Claim 8
Dependent Claim
32 words
The adsorbent of Claim 4, wherein said anionic functional group-containing compound contains at least one anionic functional group selected from the group consisting of carboxyl group, sulfonic acid group and sulfate group.
Claim 9
Dependent Claim
14 words
The adsorbent of Claim 4, wherein said anionic functional group-containing compound is a polyanion.
Claim 10
Dependent Claim
27 words
The adsorbent of Claim l, wherein a sulfate group is introduced into said gel by sulfuric esterification of hydroxyl group in a hydroxyl group-containing water-insoluble porous gel.
Claim 11
Dependent Claim
14 words
l0. The adsorbent of Claim l, wherein said gel comprises a sulfate group-containing compound.
Claim 12
Dependent Claim
13 words
The adsorbent of Claim l0, wherein said sulfate group-containing compound is sulfated polysaccharide.
Claim 13
Independent Claim
58 words
An apparatus for removing a complement component and/or an activated complement component from body fluid, which comprises a container having a inlet and an outlet for body fluid and an adsorbent packed in said container, said adsorbent comprising a water-insoluble porous gel having an anionic functional group at least on a part of the surface of said gel.
Claim 14
Independent Claim
58 words
An apparatus for removing a complement component and/or an activated complement component from body fluid, which comprises a container having a inlet and an outlet for body fluid and an adsorbent packed in said container, said adsorbent comprising a water-insoluble porous gel having an anionic functional group at least on a part of the surface of said gel.
Claim 15
Dependent Claim
75 words
A process for removing a complement component and/or an activated complement component from body fluid which comprises passing body fluid containing a complement component and/or an activated complement component through a removing apparatus, said apparatus comprising a container having a inlet and an outlet for body fluid and an adsorbent packed in said container comprising a water-insoluble porous gel having an anionic functional group at least on a part of the surface of said gel.
Claim 16
Dependent Claim
75 words
A process for removing a complement component and/or an activated complement component from body fluid which comprises passing body fluid containing a complement component and/or an activated complement component through a removing apparatus, said apparatus comprising a container having a inlet and an outlet for body fluid and an adsorbent packed in said container comprising a water-insoluble porous gel having an anionic functional group at least on a part of the surface of said gel.
Claim 17
Dependent Claim
27 words
The process of Claim l3, wherein a sulfate group is introduced into said gel by sulfuric esterification of hydroxyl group in a hydroxyl group-containing water-insoluble porous gel.
References Cited (Backward Citations)
No citation records indexed.
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