EP0223245A2
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EP
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Curable compositions for dental drugs having sustained release property
Assignee: Mitsui Chemicals Inc
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Filing: 1986-11-19
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Granted: —
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Expires: 2006-11-19
Abstract
Abstract A crude drug ingredient having bactericidal activity is incorporated into a curable composition comprising a (meth)acrylate type monomer, a polymerization initiator and if necessary a filler to formulate the ingredient into the drug having sustained release property. The curable composition containing the crude drug ingredient is applied to a defective part of a tooth or an artificial gum for preventing dental diseases such as carious tooth, pyorrhea alveolaris, etc.
Inventors
- 👤 Mitsuru Atsuta
- 👤 Takeshi Sakashita
- 👤 Ryoichi Miyamoto
- 👤 Yukinori Tanimura
- 👤 Saburo Fuji
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-26 14:59
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0063; A61K6/00; A61K6/60; A61K6/62; A61K6/64; A61K6/69; A61K9/20; A61K9/2004; A61K9/2022; A61K9/2027; Y; Y10; Y10S; Y10S522/00; Y10S522/908
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
29 words
A curable composition for dental drugs having sustained release property, which comprises (a) (meth)acrylate type monomer, (b) a polymerization initiator, and (c) a crude drug ingredient having bactericidal activity.
Claim 2
Dependent Claim
29 words
A curable composition for dental drugs having sustained release property, which comprises (a) (meth)acrylate type monomer, (b) a polymerization initiator, and (c) a crude drug ingredient having bactericidal activity.
Claim 3
Dependent Claim
34 words
The composition of claim 1 which contains, based on 100 parts by weight of the component (a), 0.01-15 parts by weight of the component (b) and 0.01-50 parts by weight of the component (c).
Claim 4
Dependent Claim
22 words
The composition of claim 1 where the component (a) is an acrylate monomer having two or more acryloyloxy groups per one molecule.
Claim 5
Dependent Claim
22 words
The composition of claim 1 wherein the component (a) is a methacrylate monomer having two or more methacryloyloxy groups per one molecule.
Claim 6
Dependent Claim
28 words
The composition of claim 4 wherein the component (a) is at least one member selected from the group consisting of di(methacryloxyethyl)trimethylhexamethylenediurethane, triethylene glycol dimethacrylate, 1,3-bis(methacryloyloxyethoxy)benzene, 2,2-bis(2-methacryloyloxyethoxyphenyl)propane and 2,2-bis(2-methacryloyloxydiethoxyphenyl)propane.
Claim 7
Dependent Claim
14 words
The composition of claim 1 wherein the component (b) is a thermal polymerization initiator.
Claim 8
Dependent Claim
13 words
The composition of claim 1 wherein the component (b) is a photopolymerization initiator.
Claim 9
Dependent Claim
12 words
The composition of claim 1 wherein the component (b) further contains amines.
Claim 10
Dependent Claim
23 words
The composition of claim 1 wherein the component (c) is selected from the group consisting of flavonoids, benzenecarboxylic acids, benzopyrones, steroids and terpenes.
Claim 11
Dependent Claim
28 words
The composition of claim 9 wherein the component (c) is selected from the group consisting of flavanone, naringenin, quercetin, anisic acid, acetyl coumarin, sitosterol, caryophyllene and caryophyllene oxide.
Claim 12
Dependent Claim
32 words
A curable composition for dental drugs having sustained release property, which comprises (a) (meth)acrylate type monomer, (b) a polymerization initiator, (c) a crude drug ingredient having bactericidal activity, and (d) a filler.
Claim 13
Dependent Claim
32 words
A curable composition for dental drugs having sustained release property, which comprises (a) (meth)acrylate type monomer, (b) a polymerization initiator, (c) a crude drug ingredient having bactericidal activity, and (d) a filler.
Claim 14
Dependent Claim
42 words
The composition of claim 11 which contains, based on 100 parts by weight of the component (a), 0.01-15 parts by weight of the component (b), 0.01-50 parts by weight of the component (c) and 1-1000 parts by weight of the component (d).
Claim 15
Dependent Claim
22 words
The composition of claim 11 wherein the component (a) is an acrylate monomer having two or more acryloyloxy groups per one molecule.
Claim 16
Dependent Claim
22 words
The composition of claim 11 wherein the component (a) is a methacrylate monomer having two or more methacryloyloxy groups per one molecule.
Claim 17
Dependent Claim
28 words
The composition of claim 14 wherein the component (a) is at least one member selected from the group consisting of di(methacryloxyethyl)trimethylhexamethylenediurethane, triethylene glycol dimethacrylate, 1,3-bis(methacryloyloxyethoxy)benzene, 2,2-bis(2-methacryloyloxyethoxyphenyl)propane and 2,2-bis(2-methacryloyloxydiethoxyphenyl)propane.
Claim 18
Dependent Claim
14 words
The composition of claim 11 wherein the component (b) is a thermal polymerization initiator.
Claim 19
Dependent Claim
13 words
The composition of claim 11 wherein the component (b) is a photopolymerization initiator.
Claim 20
Dependent Claim
12 words
The composition of claim 11 wherein said component (b) further contains amines.
Claim 21
Dependent Claim
23 words
The composition of claim 11 wherein the component (c) is selected from the group consisting of flavonoids, benzencarboxylic acids, benzopyrones, steroids and terpenes.
Claim 22
Dependent Claim
28 words
The composition of claim 19 wherein the component (c) is selected from the group consisting of flavanone, naringenin, quercetin, anisic acid, acetyl coumarin, sitosterol, caryophyllene and caryophyllene oxide.
Claim 23
Dependent Claim
29 words
The composition of claim 11 wherein the component (d) is an inorganic filler such as glass powder, silica, fused silica, ultrafine silica, alumina, silica alumina, titania, zirconia and zeolite.
Claim 24
Dependent Claim
32 words
The composition of claim 11 wherein the component (d) is an organic composite filler obtained by coating glass powder, glass bead-like silica, fused silica or ultrafine silica with a methacrylate type polymer.
Claim 25
Dependent Claim
17 words
A cured product wherein the composition of claim 1 or 11 is polymerized by a light irradiation.
Claim 26
Dependent Claim
15 words
A cured product wherein the composition of claim 1 or 11 is polymerized by heat.
Claim 27
Dependent Claim
13 words
A cured product wherein the composition of claim 8 or 18 is cured.
Claim 28
Dependent Claim
32 words
A method of preventing dental diseases such as carious tooth, pyorrhea alveolaris, etc. which comprises applying the composition of claim 1 to a defective part of a tooth or an artificial gum.
Claim 29
Dependent Claim
32 words
A method of preventing dental diseases such as carious tooth, pyorrhea alveolaris etc. which comprises applying the composition of claim 11 to a defective part of a tooth or an artificial gum.
References Cited (Backward Citations)
No citation records indexed.
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