EP0220825A2
Expired / Lapsed
EP
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Pharmaceutical composition for topical application
Assignee: Diomed Developments Ltd
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Filing: 1986-09-18
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Granted: —
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Expires: 2006-09-18
Abstract
Abstract Compositions for topical application useful for preventing pressure sores comprise a slow-acting nicotinate ester, e.g. hexyl nicotinate, in a concentration and formulation insufficient to cause observable erythema but sufficient to promote peripheral blood flow. The composition may also comprise usual ingredients in compositions for topical application to the skin.
Inventors
- 👤 Martin Whitefield
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-09 16:15
CPC Classifications
A; A61; A61K; A61K47/00; A61K47/06; A61K47/08; A61K47/12; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/455; A61K47/10; A61K9/00; A61K9/0012; A61K9/0014
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
41 words
A pharmaceutical composition for topical application comprising a slow-acting nicotinate ester in a concentration sufficient to cause increased blood cell flux in an epidermal area to which the same composition is applied, but insufficient to cause erythema, and an appropriate vehicle.
Claim 2
Dependent Claim
41 words
A pharmaceutical composition for topical application comprising a slow-acting nicotinate ester in a concentration sufficient to cause increased blood cell flux in an epidermal area to which the same composition is applied, but insufficient to cause erythema, and an appropriate vehicle.
Claim 3
Dependent Claim
14 words
A composition according to claim l in which the nicotinate ester is hexyl nicotinate.
Claim 4
Dependent Claim
32 words
A composition according to claim l or 2 in which the said nicotinate ester is present in a concentration from 0.025 to 0.075% by weight based on the weight of the composition.
Claim 5
Dependent Claim
17 words
A composition according to any one of claims l to 3 which also contain a zinc supplement.
Claim 6
Dependent Claim
29 words
A composition according to claim 4 in which the zinc supplement is present in a concentration of 0.5 to 2% by weight based on the weight of the composition.
Claim 7
Dependent Claim
21 words
A composition according to any of claims l to 5 in which the vehicle comprises stearic acid, cetostearyl alcohol and water.
Claim 8
Dependent Claim
43 words
A composition according to claim 6 in which the vehicle comprises 2 to l0% by weight of stearic acid and 2 to l0% by weight of cetostearyl alcohol, based on the total weight of the composition, the balance of the composition being water.
Claim 9
Dependent Claim
28 words
A composition according to any one of claims l to 7 which also contains one or more of a cationic bactericide, an oil soluble polysiloxane, and a lubricant.
Claim 10
Dependent Claim
44 words
A composition according to claim 8 which contains 0.5 to 2% of cetrimide as cationic bactericide, 5 to l0% of an oil polysiloxane, and 5 to l5% of isopropyl myristate, the said percentages being by weight based on the total weight of the composition.
Claim 11
Dependent Claim
30 words
l0. Use of hexyl nicotinate or other slow-acting nicotinate ester in the preparation of a pharmaceutical composition for use in therapy to promote peripheral blood flow without causing observable erythema.
Claim 12
Dependent Claim
30 words
l0. Use of hexyl nicotinate or other slow-acting nicotinate ester in the preparation of a pharmaceutical composition for use in therapy to promote peripheral blood flow without causing observable erythema.
References Cited (Backward Citations)
No citation records indexed.
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