EP0220152A1
Expired / Lapsed
EP
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Fat emulsion
Assignee: Pfizer Health AB
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Filing: 1986-10-23
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Granted: —
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Expires: 2006-10-23
Abstract
Abstract The invention concerns fat emulsions for intravenous adminstration for nutritive, diagnostic or therapeutic purposes, or for tissue culture and storage of organ transplants. According to the invention, the emulsion contains one or more substances preventing or retarding aggregation or agglutination ("creaming") when the emulsion is mixed with blood, serum or plasma.
Inventors
- 👤 Arvid Wretlind
- 👤 Bengt Ajaxon
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 10:41
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0026; A61K9/0029
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
70 words
A fat emulsion of the type oil-in-water, characterized in that it contains at least one compound which prevents creaming for at least 3 hours when the emulsion is mixed with human serum or plasma to a concentration of 1-10 percent by volume, the human serum or plasma used being such that it creates creaming within 15 minutes when mixed with 1-10 percent by volume of an emulsion of the composition
Claim 2
Dependent Claim
70 words
A fat emulsion of the type oil-in-water, characterized in that it contains at least one compound which prevents creaming for at least 3 hours when the emulsion is mixed with human serum or plasma to a concentration of 1-10 percent by volume, the human serum or plasma used being such that it creates creaming within 15 minutes when mixed with 1-10 percent by volume of an emulsion of the composition
Claim 3
Dependent Claim
38 words
Emulsion according to claim 1, characterized in that the compound consists of a carboxylic or sulfonic acid, optionally containing one or more double bonds, and having up to 20 carbon atoms, or a salt thereof or of urea.
Claim 4
Dependent Claim
24 words
Emulsion according to claim 1 or 2, characterized in that the carboxylic or sulfonic acid contains at least one amino group in its molecule.
Claim 5
Dependent Claim
33 words
Emulsion according to claim 1 or 2, characterized in that the compound consists of isovaleric acid, pelargonic acid, oleic acid, linoleic acid, linolenic acid or the sodium salt of ethylene diamine tetraacetic acid.
Claim 6
Dependent Claim
19 words
Emulsion according to claim 1 or 3, characterized in that the compound consists of glycine, serine, phenylalanine or taurine.
Claim 7
Dependent Claim
23 words
Emulsion according to any one of claims 1-5, characterized in that the compound is included in a concentration of 0.05-5 percent by weight.
Claim 8
Dependent Claim
22 words
Emulsion according to any one of claims 1-6, characterized in that it contains glycerol in a concentration of 2-30 percent by volume.
Claim 9
Dependent Claim
19 words
Emulsion according to any one of claims 1-7, characterized in that it contains at least one pharmacologically active agent.
Claim 10
Dependent Claim
27 words
Emulsion according to any one of claims 1-8 characterized in that it contains at least one perfluorinated hydrocarbon compound in a concentration of 2-30 percent by weight.
Claim 11
Dependent Claim
24 words
Emulsion according to any one of claims 1-9, characterized in that the fat consists of an animal and/or vegetable fat and/or the corresponding triglycerides.
Claim 12
Dependent Claim
26 words
Emulsion according to any one of claims 1-10, characterized in that it contains essential and/or non-essential amino acids in a concentration of 2-10 percent by weight.
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