EP0219838A2
Expired / Lapsed
EP
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Carbocyclic purine nucleosides, their production and use
Assignee: Takeda Pharmaceutical Co Ltd
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Filing: 1986-10-18
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Granted: —
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Expires: 2006-10-18
Abstract
Abstract The carbocyclic analogs to purine nucleosides represented by the formula wherein R₁ and R₂ each is a hydroxyl group, which may optionally be protected, X is a hydrogen atom or a hydroxyl group, which may optionally be protected, and Y is guanin-9-yl, isoguanin-9-yl or hypoxanthin-9-yl are useful for the treatment of viral infections and as substitutes for purine nucleosides in the field of genetic engineering, biochemistry or the like.
Inventors
- 👤 Yoshio Taniyama
- 👤 Ryuji Marumoto
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-29 03:50
CPC Classifications
C; C07; C07D; C07D473/00; C07D233/00; C07D233/54; C07D233/66; C07D233/90; C07D405/00; C07D405/02; C07D405/04; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/0834; C07F7/0838
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
58 words
A compound of the formula wherein R₁ and R₂ each is a hydroxyl group, which may optionally be protected, X is a hydrogen atom or a hydroxyl group, which may optionally be protected, and Y is guanin-9-yl, isoguanin-9-yl or hypoxanthin-9-yl, provided that when X is a hydroxyl group, which may optionally be protected, Y is other than hypoxanthin-9-yl.
Claim 2
Dependent Claim
58 words
A compound of the formula wherein R₁ and R₂ each is a hydroxyl group, which may optionally be protected, X is a hydrogen atom or a hydroxyl group, which may optionally be protected, and Y is guanin-9-yl, isoguanin-9-yl or hypoxanthin-9-yl, provided that when X is a hydroxyl group, which may optionally be protected, Y is other than hypoxanthin-9-yl.
Claim 3
Dependent Claim
24 words
The compound according to claim 1, wherein R₁ and R₂ each is a hydroxyl group, X is a hydrogen atom and Y is guanin-9-yl.
Claim 4
Dependent Claim
23 words
The compound according to claim 1, wherein R₁ and R₂ is a hydroxyl group, X is a hydrogen atom and Y is isoguanin-9-yl.
Claim 5
Dependent Claim
24 words
The compound according to claim 1, wherein R₁ and R₂ each is a hydroxyl group, X is a hydrogen atom and Y is hypoxanthin-9-yl.
Claim 6
Dependent Claim
20 words
The compound according to claim 1, wherein R₁, R₂ and X each is a hydroxyl group and Y is guanin-9-yl.
Claim 7
Independent Claim
82 words
A method of producing compounds of the formula wherein R₁ and R₂ is a hydroxyl group, which may optionally be protected, X is a hydrogen atom or a hydroxyl group, which may optionally be protected, and Y is guanin-9-yl, isoguanin-9-yl or hypoxanthin-9-yl, provided that when X is a hydroxyl group, which may optionally be protected, Y is other than hypoxanthin-9-yl, which comprises subjecting a compound of the formula wherein R₁, R₂ and X are as defined above, to purine ring formation reaction.
Claim 8
Independent Claim
82 words
A method of producing compounds of the formula wherein R₁ and R₂ is a hydroxyl group, which may optionally be protected, X is a hydrogen atom or a hydroxyl group, which may optionally be protected, and Y is guanin-9-yl, isoguanin-9-yl or hypoxanthin-9-yl, provided that when X is a hydroxyl group, which may optionally be protected, Y is other than hypoxanthin-9-yl, which comprises subjecting a compound of the formula wherein R₁, R₂ and X are as defined above, to purine ring formation reaction.
Claim 9
Dependent Claim
19 words
A compound of the formula wherein R₁ and R₂ each is a hydroxyl group, which may optionally be protected.
Claim 10
Dependent Claim
19 words
A compound of the formula wherein R₁ and R₂ each is a hydroxyl group, which may optionally be protected.
Claim 11
Dependent Claim
39 words
An antiviral composition containing a compound of the formula wherein X₁ is a hydrogen atom or a hydroxyl group, and Y is guanin-9-yl, isoguanin-9-yl or hypoxanthin-9-yl, provided that when X₁ is a hydroxyl group, Y is other than hypoxanthin-9-yl.
Claim 12
Dependent Claim
39 words
An antiviral composition containing a compound of the formula wherein X₁ is a hydrogen atom or a hydroxyl group, and Y is guanin-9-yl, isoguanin-9-yl or hypoxanthin-9-yl, provided that when X₁ is a hydroxyl group, Y is other than hypoxanthin-9-yl.
Claim 13
Dependent Claim
16 words
The composition according to claim 8, wherein X₁ is a hydrogen atom and Y is guanin-9-yl.
References Cited (Backward Citations)
No citation records indexed.
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