EP0219220A1
Expired / Lapsed
EP
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Method and composition for the simultaneous cleaning and disinfecting of contact lenses
Assignee: Allergan Inc
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Filing: 1986-09-08
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Granted: —
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Expires: 2006-09-08
Abstract
Abstract A one step method for cleaning and disinfecting contact lenses is accomplished by immersing the lenses in a solution containing peroxide and a peroxide-active enzyme.
Inventors
- 👤 Stanley W. Huth
- 👤 Sam W. Lam
- 👤 Richard M. Kiral
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-05 20:21
CPC Classifications
B; B08; B08B; B08B3/00; B08B3/04; B08B3/08; C; C11; C11D; C11D3/00; C11D3/16; C11D3/38; C11D3/386; C11D3/38609; A; A61; A61L; A61L12/00; A61L12/08; A61L12/12; A61L12/124; A61L2/00; A61L2/16; A61L2/18; C11D3/0005; C11D3/0078; C11D3/39; C11D3/3942
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
47 words
A method for simultaneously cleaning and disinfecting contact lenses which method comprises contacting a lens with a solution comprising a disinfecting amount of peroxide and an effective amount of peroxide-active proteolytic enzyme for a time sufficient to remove substantially all protein accretions and to disinfect the lenses.
Claim 2
Independent Claim
47 words
A method for simultaneously cleaning and disinfecting contact lenses which method comprises contacting a lens with a solution comprising a disinfecting amount of peroxide and an effective amount of peroxide-active proteolytic enzyme for a time sufficient to remove substantially all protein accretions and to disinfect the lenses.
Claim 3
Dependent Claim
17 words
The method of claim 1 wherein the solution is buffered to a pH between 6 and 10.
Claim 4
Dependent Claim
25 words
The method of claim 2 wherein the proteolytic enzyme is subtilisin, pancreatin or trypsin in an amount between 0.0003 and 0.05 Anson units per ml.
Claim 5
Independent Claim
43 words
The method of any of claims 1 to 3 wherein the enzyme is present in an amount between 0.0001 and 0.5 Anson units per ml and the peroxide is hydrogen peroxide which is present in an amount between 0.05 and 10% by weight/volume.
Claim 6
Dependent Claim
21 words
The method of claim 4 where the solution comprises 3% hydrogen peroxide and 0.0012 Anson units per ml of subtilisin A.
Claim 7
Independent Claim
28 words
The method of any of claims 1 to 3 wherein the peroxide is the salt of a perborate, persulfate, percarbonate, diperisophthalic acid, peroxydiphosphate or an aluminium aminohydroperoxide salt.
Claim 8
Dependent Claim
35 words
The method of claim 6 wherein the enzyme is present in an amount between 0.0001 and 0.5 Anson units per ml and the peroxide is present in an amount of 0.02% by weight/volume or greater.
Claim 9
Dependent Claim
38 words
The method of claim 7 wherein the peroxide is sodium perborate, potassium persulfate, sodium percarbonate, diperisophthalic acid, peroxydiphosphate salts or sodium aluminium aminohydroperoxide and the enzyme is subtilisin A in the amount of 0.0012 Anson units per ml.
Claim 10
Dependent Claim
26 words
The method of claim 1 wherein the solution is prepared by combining the enzyme and peroxide at the time the lenses are contacted with the solution.
Claim 11
Dependent Claim
56 words
A process for preparing a solution as defined in any one of claims 1-8, the peroxide and peroxide-active enzyme being present in amounts such that when the peroxide is reduced, the resulting solution has an osmolality in the range 150-600 mOsm/kg, which process comprises bringing into admixture in aqueous solution the peroxide and the peroxide-active enzyme.
Claim 12
Dependent Claim
25 words
A process according to claim 10 for preparing a solution which, when the peroxide has been reduced, has an osmolality in the range 200-350 mOsm/kg.
Claim 13
Dependent Claim
85 words
A process for preparing a tablet containing 25-35% (w/w) sorbitol, 17.5-27.5% (w/w) N-acetylcysteine, 34-44% (w/w) sodium carbonate, 0-8% - (w/w) polyethylene glycol 3350, 0.1-0.5% (w/w) subtilisin A and 1-10% (w/w) tartaric acid, said tablet being capable, when added to an aqueous hydrogen peroxide solution, of forming a solution as defined in claim 1, which process comprises bringing into admixture the sorbitol, N-acetylcysteine, sodium carbonate, polyethylene glycol 3350, subtilisin A and tartaric acid and then forming the mixture into a tablet by methods known per se.
Claim 14
Dependent Claim
29 words
A process according to claim 12 wherein the tablet contains approximately 30% sorbitol, 22.5% N-acetylcysteine, 39% sodium carbonate, 3% polyethylene glycol 3350, 0.3% subtilisin A and 5.2% tartaric acid.
References Cited (Backward Citations)
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