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EP0216362A2
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Stable freeze-dried preparation of an anticancer platinum complex
Assignee: Shionogi and Co Ltd
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Filing: 1986-09-24
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Granted: —
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Expires: 2006-09-24
Abstract
Abstract Stable freeze-dried preparations of an anticancer platinum complex, i.e. glycolato-cis-diammineplatinum (II) containing at least one stabilizer selected from the group consisting of glucan, water-soluble vinyl polymer, and polyethylene glycol, are very useful in the treatment of various cancers.
Inventors
- 👤 Kazuhiro Shima
- 👤 Takayuki Tsukada
- 👤 Hirotane Kagawa
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-24 17:56
CPC Classifications
A; A61; A61K; A61K33/00; A61K33/24; A61K47/00; A61K47/30; A61K47/36; A61K31/00; A61K31/28; A61K47/06; A61K47/08; A61K47/10; A61K47/32; A61K9/00; A61K9/14; A61K9/19; A61P; A61P35/00
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
23 words
A freeze-dried preparation of glycolato-cis-diammineplatinum (II) as the active ingredient containing at least one glucan, water-soluble vinyl polymer and/or polyethylene glycol as stabilizer.
Claim 2
Dependent Claim
23 words
A freeze-dried preparation of glycolato-cis-diammineplatinum (II) as the active ingredient containing at least one glucan, water-soluble vinyl polymer and/or polyethylene glycol as stabilizer.
Claim 3
Dependent Claim
15 words
A freeze-dried preparation claimed in Claim 1 wherein the glucan is a water-soluble neutral glucan.
Claim 4
Dependent Claim
18 words
A freeze-dried preparation claimed in Claim 1 wherein the glucan is a water-soluble modified starch or its derivative.
Claim 5
Dependent Claim
15 words
A freeze-dried preparation claimed in Claim 1 wherein the glucan is a water-soluble cellulose derivative.
Claim 6
Dependent Claim
17 words
A freeze-dried preparation claimed in Claim 2 wherein the water-soluble neutral glucan is dextran, pullulan, or amylose.
Claim 7
Dependent Claim
14 words
A freeze-dried preparation claimed in Claim 2 wherein the water-soluble neutral glucan is dextran.
Claim 8
Dependent Claim
23 words
A freeze-dried preparation claimed in Claim 3 wherein the water-soluble modified starch or its derivative is dextrin, cyclodextrin, soluble starch, or hydroxyethyl starch.
Claim 9
Dependent Claim
25 words
A freeze-dried preparation claimed in Claim 4 wherein the water-soluble cellulose derivative is methyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, or carboxymethyl cellulose sodium salt.
Claim 10
Dependent Claim
18 words
A freeze-dried preparation claimed in Claim 1 wherein the water-soluble vinyl polymer is polyvinyl alcohol or polyvinyl pyrrolidone.
Claim 11
Dependent Claim
25 words
1C. A freeze-dried preparation claimed in Claim 1 which contains the stabilizers at a ratio of 0.05-5 weight-parts to 1 weight-part of said active ingredient.
Claim 12
Dependent Claim
24 words
A freeze-dried preparation claimed in Claim 1 which contains the stabilizers at a ratio of 0.1-3 weight-parts to 1 weight-part of said active ingredient.
References Cited (Backward Citations)
No citation records indexed.
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