EP0198628A1
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Device and method for whole blood separation and analysis
Assignee: SmithKline Diagnostics Inc
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Filing: 1986-04-01
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Granted: —
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Expires: 2006-04-01
Abstract
Abstract A method and device (10) for separating blood into fluid and cellular fractions for diagnostic tests. The whole blood (34) is introduced to a carrier (36) containing a layer of carbohydrate and reagent material which results in the rapid separation of the fluid (38A) from the cellular fractions (38). In a preferred embodiment, the device is fabricated in a sandwich design containing the layers of carbohydrate and reagent material between two layers of plastic.
Inventors
- 👤 Myron Colman Rapkin
- 👤 Ronald Joseph Schoengold
- 👤 David Ray Shockey
- 👤 Pierre Charles Van Rysselberghe
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-30 13:33
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/521; G01N33/523; Y; Y10; Y10S; Y10S435/00; Y10S435/805; Y10T; Y10T436/00; Y10T436/25; Y10T436/25375; Y10T436/255
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
28 words
A test device for separating whole blood into fluid and cellular portions and for detecting soluble components in whole blood comprising a carrier having applied thereto a carbohydrate.
Claim 2
Dependent Claim
28 words
A test device for separating whole blood into fluid and cellular portions and for detecting soluble components in whole blood comprising a carrier having applied thereto a carbohydrate.
Claim 3
Dependent Claim
16 words
The test device of claim 1 wherein a test reagent is further applied to said carrier.
Claim 4
Dependent Claim
12 words
The device of claim 1 wherein said carrier is a permeable carrier.
Claim 5
Dependent Claim
11 words
The device of claim 3 wherein the carrier is filter paper.
Claim 6
Dependent Claim
10 words
The device of claim 1 wherein said carrier is impermeable.
Claim 7
Dependent Claim
30 words
The device of claim 5 wherein the carrier is selected from the group consisting of polyesters, polycarbonates, polystyrenes, polyvinyl polymers, polypropylene, polyethylene, polyethylene terephthalate, ethylcellulose, cellophane, glass, and wax paper.
Claim 8
Dependent Claim
62 words
A test device for separating the fluid portion from whole blood and detecting soluble components in whole blood which comprises a first carrier having applied thereon a carbohydrate and layered to said first carrier, a second carrier having incorporated thereon a test reagent specifically reactable with said component, said device having an opening through which the blood sample can contact the carbohydrate.
Claim 9
Dependent Claim
62 words
A test device for separating the fluid portion from whole blood and detecting soluble components in whole blood which comprises a first carrier having applied thereon a carbohydrate and layered to said first carrier, a second carrier having incorporated thereon a test reagent specifically reactable with said component, said device having an opening through which the blood sample can contact the carbohydrate.
Claim 10
Dependent Claim
23 words
The device of claim 7 wherein the first and second carriers are layered so that the carbohydrate and reagent are in contiguous relationship.
Claim 11
Dependent Claim
10 words
The device of claim 7 wherein the carriers are impermeable.
Claim 12
Dependent Claim
19 words
The device of claim 9 wherein the first carrier is a polyester and the second carrier is a polycarbonate.
Claim 13
Dependent Claim
18 words
ll. The device of claim 9 wherein the first carrier is opaque and the second carrier is transparent.
Claim 14
Dependent Claim
11 words
The device of claim 7 wherein the carbohydrate is a sugar.
Claim 15
Dependent Claim
10 words
The device is claim 12 wherein the sugar is mannitol.
Claim 16
Independent Claim
46 words
A method for separating whole blood into fluid and cellular fractions which comprises applying the blood to a carrier containing a layer of carbohydrate whereby the cellular fraction remains in close proximity to the site of contact and the fluid fraction migrates away from said site.
Claim 17
Independent Claim
46 words
A method for separating whole blood into fluid and cellular fractions which comprises applying the blood to a carrier containing a layer of carbohydrate whereby the cellular fraction remains in close proximity to the site of contact and the fluid fraction migrates away from said site.
Claim 18
Dependent Claim
10 words
The method of claim 14 wherein the carbohydrate is mannitol.
Claim 19
Dependent Claim
10 words
The method of claim 15 wherein the carrier is permeable.
References Cited (Backward Citations)
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