EP0196546A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Pharmaceutical tableting method
Assignee: Abbott Laboratories
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Filing: 1986-03-18
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Granted: —
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Expires: 2006-03-18
Abstract
Abstract A method of preventing the fracture of coated drug granules during the compression of the granules into a commerically acceptable tablet matrix is discosed. The method involves incorporating into the matrix, along with the granules, from about 10% to about 50% by weight microcrystalline cellulose.
Inventors
- 👤 Wallace E. Becker
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-02 23:07
CPC Classifications
A; A61; A61J; A61J3/00; A61J3/10; A61K; A61K9/00; A61K9/20; A61K9/2072; A61K9/2077; A61K9/2081
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
64 words
A method of preventing the fracture of friable coated drug granules during the compression of the granules into a tablet matrix having a hardness sufficient to resist an applied fracturing pressure of of at least 15 kg/in , comprising the step of incorporating into the matrix, along with the granules, from about 10% to about 50% microcrystalline cellulose, by weight of the total matrix.
Claim 2
Independent Claim
64 words
A method of preventing the fracture of friable coated drug granules during the compression of the granules into a tablet matrix having a hardness sufficient to resist an applied fracturing pressure of of at least 15 kg/in , comprising the step of incorporating into the matrix, along with the granules, from about 10% to about 50% microcrystalline cellulose, by weight of the total matrix.
Claim 3
Dependent Claim
13 words
A method according to Claim 1 wherein the granules have an enteric coating.
Claim 4
Dependent Claim
14 words
A method according to Claim 2 wherein the matrix further comprises noncoated drug granules.
Claim 5
Dependent Claim
19 words
A method according to Claim 3 wherein the noncoated granules comprise the same drug as the friable coated granules.
Claim 6
Dependent Claim
23 words
A method according to Claim 3 wherein the noncoated drug granules contain a drug different from the drug in the friable coated granules.
References Cited (Backward Citations)
No citation records indexed.
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