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EP0192327A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Use of phosphonoformic acid and its esters and salts for the manufacture of a medicament for the treatment of AIDS

Assignee: Wellcome Foundation Ltd
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Filing: 1986-01-17
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Granted: —
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Expires: 2006-01-17
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Abstract

Abstract The present invention relates to the use of phosphono- formic acid, its esters and salts, in the treatment of acquired immune deficiency syndrome (AIDS).

Inventors

  • 👤 Martha Heider St-Clair
  • 👤 Phillip Allen Furman
  • 👤 David Walter Barry

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-08 01:00
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/66; A61P; A61P37/00; A61P37/02; A61P37/04

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 98 words
I. Use of a compound of formula (I) (wherein R I , R2, and R 3 may be the some or different and each is selected from hydrogen, C 1-6 alkyl, C 3-6 cycloalkyl, C 4-7 cycloalkyalkyl, benzyl and phenyl having up to three optional substituents selected from halogen, C 1-4 alkyl, C 1-4 alkoxy, C 2-7 alkoxycarbonyl and C 2-7 alkylcarbonyl and, when at least one of R 1 , R 2 and R 3 is hydrogen, pharmaceutically acceptable salts thereof) in the manufacture of a medicament for the treatment or prophylaxis of acquired immune deficiency syndrome.
Claim 2
Dependent Claim 25 words
Use of a compound of formula (I) as claimed in claim 1 wherein R 1 , R 2 , and R 3 each represent hydrogen.
Claim 3
Dependent Claim 30 words
Use of a pharmaceutically acceptable salt of a compound of formula (I) as claimed in claim I wherein R I , R 2 , and R 3 each represent hydrogen.
Claim 4
Dependent Claim 27 words
Use of a compound of formula (I) as claimed in any of claims I to 3 wherein the said salt is selected from mono, di- and triphosphate.
Claim 5
Dependent Claim 26 words
S. Use of a compound of formula (I) as claimed in any of claims 1 to 4 wherein the said medicament is adapted for intravenous administration.
Claim 6
Dependent Claim 29 words
Use of a compound of formula (I) as claimed in any of claims 1 to 4 wherein the said medicament is in the form of a tablet or capsule.
Claim 7
Dependent Claim 32 words
A compound of formula (I) or a pharmaceutically acceptable salt thereof (as defined in any of claims 1 to 4) for use in the treatment or prophylaxis of acquired immune deficiency syndrome.
Claim 8
Dependent Claim 35 words
A compound of formula (I) or a pharmaceutically acceptable salt thereof (as defined in any of claims I to 4) for use in the treatment or prophylaxis of an HTLV-III infection in a human being.

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