LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues

Abstract

Abstract A conjugate between a nona- or decapeptide of the formula i) or ii):i) Lys-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂, orii) Cys-Lys-Trp-Ser-Try-Gly-Leu-Arg-Pro-Gly-NH₂, or mixtures of peptides i) and ii).and a protein in provided which, when used per se or when mixed with a suitable adjuvant, yields a vaccine which acts as an immunogen for LHRH and induces a mammal to produce antibodies which react with LHRH. Immunization against the body's LHRH results in lowering of male and female sex hormones including luteinizing hormone so as to prevent conception. Other uses for materials which lessen the effect of LHRH in the body are known in the art.

Inventors

• 👤 Abdus Salam Mia

Bibliographic Details