EP0180980A2
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EP
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Lipid membrane structures
Assignee: Daiichi Pharmaceutical Co Ltd
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Filing: 1985-11-06
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Granted: —
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Expires: 2005-11-06
Abstract
Abstract Lipid membrane structures being incorporated a lactose monofatty acid ester or amide are disclosed. The lipid membrane structures are delivered preferentially to the liver parenchymal cells and are useful as carriers of drugs.
Inventors
- 👤 Munehiro C/O Daiichi Seiyaku Res.Lab. Tomikawa
- 👤 Sadao C/O Daiichi Seiyaku Res.Lab. Hirota
- 👤 Hiroshi C/O Daiichi Seiyaku Res.Lab. Kikuchi
- 👤 Hitoshi C/O Daiichi Seiyaku Res.Lab. Yamauchi
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-09 05:28
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/10; A61K9/127; A61K9/1271; A61K9/1272; A61P; A61P1/00; A61P1/16; Y; Y10; Y10T; Y10T428/00; Y10T428/249921; Y10T428/249994; Y10T428/249995; Y10T428/249997
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
12 words
Lipid membrane structures being incorporated a lactose monofatty acid ester or amide.
Claim 2
Dependent Claim
12 words
Lipid membrane structures being incorporated a lactose monofatty acid ester or amide.
Claim 3
Dependent Claim
17 words
Lipid membrane structures as in Claim 1, wherein said lipid membrane structures are liposomes, micelles or microemulsions.
Claim 4
Dependent Claim
41 words
Lipid membrane structures as in Claim 1, wherein said lactose monofatty acid ester is a compound wherein an acyl group having from 12 to 30 carbon atoms is bonded to one of the hydroxyl groups of the glucose moiety of lactose.
Claim 5
Dependent Claim
38 words
Lipid membrane structures as in Claim 1, wherein said lactose monofatty acid amide is a compound wherein an acyl group having from 12 to 30 carbon atoms is bonded to the 1-position of the glucose moiety of lactose.
Claim 6
Dependent Claim
15 words
Lipid membrane structures as in Claim 1, wherein said lactose monofatty acid amide is 1-N-arachidyl-l-deoxy-lactosylamine.
Claim 7
Dependent Claim
32 words
Lipid membrane structures as in Claim 1, wherein said lactose monofatty acid ester or amide is contained at a molar ratio of at least about 1/40 based on the total lipid components.
Claim 8
Dependent Claim
29 words
Lactose monofatty acid amides in which the acyl group has 12 to 30 carbon atoms and is bonded to the glucose moiety of lactose through an acid amide linkage.
Claim 9
Dependent Claim
29 words
Lactose monofatty acid amides in which the acyl group has 12 to 30 carbon atoms and is bonded to the glucose moiety of lactose through an acid amide linkage.
Claim 10
Dependent Claim
23 words
The lactose monofatty acid amides of claim 7 in which the acyl group is bonded in 1-position of the glucose moiety of lactose.
Claim 11
Dependent Claim
39 words
A process for preparing the compounds of claim 7 and 8 characterized in that lactosylamine wherein the hydroxy groups are protected is reacted with a fatty acid having 12 to 30 carbon atoms and the protecting groups are removed.
References Cited (Backward Citations)
No citation records indexed.
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