EP0180190A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
3,4-Dihydrobenzopyran compounds and pharmaceutical composition containing the same
Assignee: Kuraray Co Ltd
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Filing: 1985-10-29
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Granted: —
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Expires: 2005-10-29
Abstract
Abstract Novel 3,4-dihydrobenzopyran compounds of the formula: wherein R 1 , R 2 and R 3 are each hydrogen or nicotinoyl group and at least one of them is nicotinoyl group, m is an integer of 0, 1 or 2, and n is an integer of 0 or 1, which is useful for prophylaxis and treatment of hyperlipemia and the compounds wherein R l and R 3 being nicotinoyl group and n is 0 being also effective for prophylaxis and treatment of hepatic diseases, and pharmaceutical composition containing said compounds as an active ingredient.
Inventors
- 👤 Koichi Kanehira
- 👤 Manzo Shiono
- 👤 Yoshiji Fujita
- 👤 Takashi Nishida
- 👤 Johji Yamahara
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-03 00:55
CPC Classifications
C; C07; C07D; C07D405/00; C07D405/02; C07D405/12; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/455; C07D405/14
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
47 words
A 3,4-dihydrobenzopyran compound of the formula: wherein A 1 , R 2 and-R 3 are each hydrogen or nicotinoyl group a and at least one of them is/nicotinoyl group, m is an integer of 0, 1 or 2, and n is an integer of 0 or 1.
Claim 2
Dependent Claim
47 words
A 3,4-dihydrobenzopyran compound of the formula: wherein A 1 , R 2 and-R 3 are each hydrogen or nicotinoyl group a and at least one of them is/nicotinoyl group, m is an integer of 0, 1 or 2, and n is an integer of 0 or 1.
Claim 3
Dependent Claim
10 words
The compound as claimed in claim 1, which is 3,4-dihydro-2-nicotinoyloxyethyl-2,5,7,8-tetramethyl-2H-benzopyran-6-ol.
Claim 4
Dependent Claim
11 words
The compound as claimed in claim 1, which is 3,4-dihydro-2-nicotinoyloxyethyl-2,5,7,8-tetramethyl-2H-benzopyran-6-yl nicotinate.
Claim 5
Dependent Claim
11 words
The compound as claimed in claim 1, which is 3,4-dihydro-2-hydroxyethyl-2,5,7,8-tetramethyl-2H-benzopyran-6-yl nicotinate.
Claim 6
Dependent Claim
10 words
The compound as claimed in claim 1, which is 3,4-dihydro-2-nicotinoyloxymethyl-2,5,7,8-tetramethyl-2H-benzopyran-6-ol.
Claim 7
Dependent Claim
11 words
The compound as claimed in claim 1, which is 3,4-dihydro-2-nicotinoyloxymethyl-2,5,7,8-tetramethyl-2H-benzopyran-6-yl nicotinate.
Claim 8
Dependent Claim
11 words
The compound as claimed in claim 1, which is 3,4-dihydro-2-nicotinoyloxypropyl-2,5,7,8-tetramethyl-2H-benzopyran-6-yl nicotinate.
Claim 9
Dependent Claim
11 words
The compound as claimed in claim 1, which is 3,4-dihydro-2-[2,3-di(nicotinoyloxy)propyl]-2,5,7,8-tetramethyl-2H-benzopyran-6-yl nicotinate.
Claim 10
Dependent Claim
37 words
A pharmaceutical composition which comprises as an active ingredient a prophylactically or therapeutically effective amount of a 3,4-dihydrobenzopyran compound I according to any of claims 1 to 8 in admixture with a pharmaceutically acceptable carrier and/or diluent.
Claim 11
Dependent Claim
17 words
The composition as claimed in claim 9, which is useful for the prophylaxis and treatment of hyperlipemia.
Claim 12
Dependent Claim
53 words
A pharmaceutical composition for the prophylaxis and treatment of hepatic diseases, which comprises as an active ingredient a prophylactically or therapeutically effective amount of a 3,4-dihydrobenzopyran compound according to claim 1 of the formula: wherein m is an integer of 0, 1 or 2, in admixture with a pharmaceutically acceptable carrier or diluent.
Claim 13
Dependent Claim
28 words
Use of a 3,4-dihydrobenzopyran compound I according to any of claims 1 to 8 for the preparation of a pharmaceutical composition for the prophylaxis and treatment of hyperlipemia.
Claim 14
Dependent Claim
37 words
Use of a 3,4-dihydrobenzopyran compound according to claim 1 of the formula: wherein m is an integer of 0, 1 or 2, for the preparation of a pharmaceutical composition for the prophylaxis and treatment of hepatic diseases.
References Cited (Backward Citations)
No citation records indexed.
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