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EP0164927A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Release devices

Assignee: Castex Products Ltd
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Filing: 1985-05-17
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Granted: —
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Expires: 2005-05-17
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Abstract

Abstract A bolus for administering a biologically active material for example an insecticide into a liquid environment such as the water of a reservoir or lake or an anthelmintic into the rumen juices of an animal comprises a succession of liquid impermeable outer segments (153, 263) enclosing a core which in the simplest case may be a single unitary active material segment (151, Figure 14) or in a developed embodiment may comprise a succession of annular segments (269, Figure 25) contained in sealed recesses (267) in the outer segments (263) which are located on a degradable central rod (265) e.g. of magnesium alloy, which itself will be active for instance to combat magnesium deficiency. As shown in Figure 25, the device may incorporate a weight (275) which, in animal use, inhabits regurgitation. Additionally, the device may include a galvanic couple element which, with the rod (265) sets up a galvanic action which controls the speed of degradation of the rod (265) and thereby the rate of administration of the segments (26).

Inventors

  • 👤 Derek James Whitehead
  • 👤 Michael Trevor Shepherd

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 23:20
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0068; A61M; A61M31/00; A61M31/002

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 72 words
A release device in the form of a generally elongate bolus having two ends and comprising a degradable core, which consists of or contains a biologically active material, surrounded by a liquid impermeable casing and exposed at one of its ends or both of its ends, characterised in that the liquid impermeable casing comprises a plurality of outer segments which are successively shed Erom the bolus as the core is progressively degraded.
Claim 2
Dependent Claim 72 words
A release device in the form of a generally elongate bolus having two ends and comprising a degradable core, which consists of or contains a biologically active material, surrounded by a liquid impermeable casing and exposed at one of its ends or both of its ends, characterised in that the liquid impermeable casing comprises a plurality of outer segments which are successively shed Erom the bolus as the core is progressively degraded.
Claim 3
Dependent Claim 20 words
A release device as claimed in claim 1 wherein the. outer segments are tubular or ring-form segments of inert material.
Claim 4
Dependent Claim 22 words
A release device as claimed in claim 2 wherein the outer segments seal relative to one another by abutting against one another.
Claim 5
Dependent Claim 20 words
A release device as claimed in claim 2 or 3 wherein sealing washers are provided between the adjacent outer segments.
Claim 6
Dependent Claim 20 words
A release device as claimed in any preceding claim wherein the core comprises a single segment of biologically active material.
Claim 7
Dependent Claim 28 words
A release device as claimed in any of claims 1 to 4 wherein the core comprises a plurality of spaced-apart disc-form or annular segments of biologically active material.
Claim 8
Dependent Claim 35 words
A release device as claimed in claim 6 wherein the biologically active material segments are separated by flanges extending inwardly from the outer segments and are penetrated by a rod of degradable or corrodible material.
Claim 9
Dependent Claim 15 words
A release device as claimed in claim 7 wherein the rod is of magnesium alloy.
Claim 10
Dependent Claim 24 words
A release device as claimed in claim 6, 7 or > 8 wherein the segments are retained relative to one another by the rod.
Claim 11
Dependent Claim 40 words
A release device as claimed in any of claims 1 to.4 wherein the core comprises biologically active material segments which are separated by further ) segments of a degradable or corrodible metal which may or may not be biologically active.
Claim 12
Dependent Claim 20 words
A release device as claimed in claim 10 wherein the degradable or corrodible metal segments are of a magnesium alloy.
Claim 13
Dependent Claim 18 words
5 12. A release device as claimed in any preceding claim and which is adapted to inhibit regurgitation.
Claim 14
Dependent Claim 43 words
A release device as claimed in claim 12 wherein regurgitation is inhibited by weighting which serves to retain the bolus in the rumen of a dosed animal until the biologically active segments and the degradable or corrodible metal segments (if provided) are spent.
Claim 15
Dependent Claim 30 words
A release device as claimed in any preceding claim wherein the biologically active material is a therapeutic agent, an anti-coccidial, a growth promotant, an anthelmintic, an insecticide or a parasiticide.
Claim 16
Dependent Claim 19 words
A release device as claimed in claim 14 wherein the biologically active material is levamisole or oxfendazole, as anthelmintic.
Claim 17
Dependent Claim 26 words
A release device as claimed in claim 14 wherein the biologically active material is Lasalocid (Trade Name) or M 139603 as anti-coccidial or a growth promoter.

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