EP0157695A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants
Assignee: Forest Laboratories LLC
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Filing: 1985-03-22
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Granted: —
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Expires: 2005-03-22
Abstract
Abstract 57 A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a controlled and prolonged release pattern upon administration, the carrier base material being a mixture of one or more nonionic cellulose ethers and an anionic surfactant, and wherein at least one of the cellulose ethers is methyl cellulose or hydroxypropylmethylcellulose having a number average molecular weight of at least 50,000.
Inventors
- 👤 Norman Grant Gaylord
- 👤 Joseph Martin Schor
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-07 21:06
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2013; A61K9/2022; A61K9/205; A61K9/2054
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
71 words
A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a controlled and prolonged release pattern upon administration, the carrier base material being a mixture of one or more water-soluble nonionic cellulose ethers and an anionic surfactant, and wherein at least one of the cellulose ethers is methylcellulose or hydroxypropylmethylcellulose having a number average molecular weight of at least 50,000.
Claim 2
Dependent Claim
71 words
A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a controlled and prolonged release pattern upon administration, the carrier base material being a mixture of one or more water-soluble nonionic cellulose ethers and an anionic surfactant, and wherein at least one of the cellulose ethers is methylcellulose or hydroxypropylmethylcellulose having a number average molecular weight of at least 50,000.
Claim 3
Dependent Claim
13 words
A composition according to claim 1 wherein the nonionic cellulose ether is methylcellulose.
Claim 4
Dependent Claim
13 words
A composition according to claim 1 wherein the nonionic cellulose ether is hydroxypropylmethylcellulose.
Claim 5
Dependent Claim
19 words
A composition according to claim 1 wherein the anionic surfactant is an alkali metal salt of an organic sulfate.
Claim 6
Dependent Claim
21 words
A composition according to claim 4 wherein the organic sulfate is selected from the group consisting of Cg-C 24 alcohol sulfates.
Claim 7
Dependent Claim
17 words
A composition according to claim 4 wherein the organic sulfate is the sulfate of an ethoxylated compound.
Claim 8
Dependent Claim
19 words
A composition according to claim 1 wherein the anionic surfactant is an alkali metal salt of an organic sulfonate.
Claim 9
Dependent Claim
14 words
A composition according to claim 7 wherein the organic sulfonate is an aryl sulfonate.
Claim 10
Dependent Claim
13 words
A composition according to claim 7 wherein the organic sulfonate is a dialkylsulfosuccinate.
Claim 11
Independent Claim
78 words
A method for the preparation of a therapeutically active solid unit dosage form having a controlled and prolonged release pattern upon administration, consisting of compressing and shaping a mixture of a therapeutically active medicament and a carrier base material consisting of a mixture of one or more water-soluble nonionic cellulose ethers and an anionic surfactant, and wherein at least one of the cellulose ethers is methylcellulose or hydroxypropylmethylcellulose having a number average molecular weight of at least 50,000.
Claim 12
Independent Claim
78 words
A method for the preparation of a therapeutically active solid unit dosage form having a controlled and prolonged release pattern upon administration, consisting of compressing and shaping a mixture of a therapeutically active medicament and a carrier base material consisting of a mixture of one or more water-soluble nonionic cellulose ethers and an anionic surfactant, and wherein at least one of the cellulose ethers is methylcellulose or hydroxypropylmethylcellulose having a number average molecular weight of at least 50,000.
References Cited (Backward Citations)
No citation records indexed.
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