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EP0154687A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Carrier plate and screening assembly for immunoassay procedures

Assignee: Becton Dickinson and Co
•
Filing: 1983-02-18
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Granted: —
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Expires: 2003-02-18
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Abstract

Abstract A carrier plate (90) useful in immunoassay procedures comprises: a generally planar support body (91); a plurality of separate, individualized pockets (94) in the body (91); and for each pocket, a removable body deposited in the respective pocket (94), each removable body (95) having a surface adapted to bind an immunogenic substance; each pocket (94) including an upper opening (98) to allow deposit of the removable body in to the respective pocket and to allow removal of the removable body from the pocket, and each pocket (94) further including a lower opening (97) which is smaller than the removable body deposited In the pocket (94) and which allows fluid to enter in to the pocket (94) while the removable body (95) is in the pocket.

Inventors

  • 👤 Bruno V. Sapatino
  • 👤 Luther R. Johnson

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-05 21:19
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5025; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/5302; G01N33/5304; G01N33/543; G01N33/544; G01N33/545; B01J; B01J2219/00; B01J2219/00274; B01J2219/00277; B01J2219/00497; B01J2219/00504

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 126 words
A carrier plate (90) useful in immunoassay procedures and comprising: a generally planar support body (91); a plurality of separate, individualized pockets (94) in the body (91); and for each pocket, a removable body deposited in the respective pocket (94), each removable body (95) having a surface adapted to bind an immunogenic substance; each pocket (94) including an upper opening (98) to allow deposit of the removable body in to the respective pocket and to allow removal of the removable body from the pocket, and each pocket (94) further including a lower opening (97) which is smaller than the removable body deposited in the pocket (94) and which allows fluid to enter in to the pocket (94) while the removable body (95) is in the pocket.
Claim 2
Dependent Claim 126 words
A carrier plate (90) useful in immunoassay procedures and comprising: a generally planar support body (91); a plurality of separate, individualized pockets (94) in the body (91); and for each pocket, a removable body deposited in the respective pocket (94), each removable body (95) having a surface adapted to bind an immunogenic substance; each pocket (94) including an upper opening (98) to allow deposit of the removable body in to the respective pocket and to allow removal of the removable body from the pocket, and each pocket (94) further including a lower opening (97) which is smaller than the removable body deposited in the pocket (94) and which allows fluid to enter in to the pocket (94) while the removable body (95) is in the pocket.
Claim 3
Dependent Claim 24 words
A carrier plate according to claim 1, wherein the lower opening (97) in each pocket (94) takes the form of one or more slots.
Claim 4
Dependent Claim 19 words
A carrier plate according to claim 1 or 2, wherein the pockets are arranged in orthogonal columns and rows.
Claim 5
Dependent Claim 11 words
A carrier plate according to claim 3, which has 96 pockets.
Claim 6
Dependent Claim 19 words
A carrier plate according to any preceding claim, wherein the pockets (94) depend downwardly from the support body (91).
Claim 7
Dependent Claim 25 words
A carrier plate according to any of claims 1 to 5, wherein the removable body (95) in each pocket is a substantially spherical plastics bead.
Claim 8
Dependent Claim 51 words
A screening assembly useful in immunoassay procedures and comprising: a carrier plate (90) as defined in any preceding claim; and a tray (100) adapted to hold fluid and adapted to receive the carrier plate in a disposition such that the removable beads can be contacted with fluid placed in the tray.
Claim 9
Dependent Claim 33 words
An assembly according to claim 7, wherein the tray (100) has a plurality of separate, individualized wells (101) arranged to align with the pockets so that there is one well for each pocket.
Claim 10
Dependent Claim 43 words
A radioimmunoassay ("RIA") for screening of hybridoma cultures for antibody production, characterized in that an assembly according to claim 7 or 8 is employed as part of the equipment for the assay, the removable bodies (94) having been contacted with the hybridoma cultures.

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