EP0154353A2
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EP
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An anti-amnestic agent
Assignee: Yakult Honsha Co Ltd
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Filing: 1985-03-08
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Granted: —
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Expires: 2005-03-08
Abstract
Abstract An anti-amnestic agent which comprises as an active ingredient thereof at least one prolinal derivative of the general formula I wherein A is a protective group for amino group in the field of amino acid chemistry and X is a residue of an amino acid, in a pharmacologically active amount together with an excipient. This agent is less toxic and can safely be administered to patients orally or intravenously for the remedy of memory disorder.
Inventors
- 👤 Daisuke Tsuru
- 👤 Tadashi Yoshimoto
- 👤 Hisao Hagiwara
- 👤 Kunio Kado
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-09 15:41
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/04; C07D207/08; A; A61; A61P; A61P25/00; A61P25/28; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
54 words
An anti-amnestic agent which comprises as an active ingredient thereof at least one prolinal derivative of the general formula I wherein A is a protective group for amino group in the field of amino acid chemistry and X is a residue of an amino acid, in a pharmacologically active amount together with an excipient.
Claim 2
Dependent Claim
54 words
An anti-amnestic agent which comprises as an active ingredient thereof at least one prolinal derivative of the general formula I wherein A is a protective group for amino group in the field of amino acid chemistry and X is a residue of an amino acid, in a pharmacologically active amount together with an excipient.
Claim 3
Dependent Claim
28 words
An anti-amnestic agent according to claim 1, wherein the protective group is selected from an N-benzyloxycarbonyl group, t-butyloxycarbonyl group and a lower acyl group with 2-4 carbon atoms.
Claim 4
Dependent Claim
31 words
An anti-amnestic agent according to claim 1, wherein the pharmacologically active amount is between 1 mg and 900 mg/Kg of body weight in terms of daily dosein case of oral administration.
Claim 5
Dependent Claim
32 words
An anti-amnestic agent according to claim l, wherein the pharmacologically active amount is between 0.5 mq and 500 mg/Kg of body weight in terms of daily dose in case of intravenous injection.
Claim 6
Dependent Claim
33 words
A prolinal derivative of the general formula I wherein A is a protective group for amino group in the field of amino acid chemistry and X is a residue of an amino acid.
Claim 7
Dependent Claim
33 words
A prolinal derivative of the general formula I wherein A is a protective group for amino group in the field of amino acid chemistry and X is a residue of an amino acid.
Claim 8
Dependent Claim
44 words
A prolinal derivative of the general formula I according to claim 5, wherein A is an N-benzyloxycarbonyl group, t-butyloxycarbonyl group or a lower acyl group with 2-4 carbon atoms and X is a residue of alanine, glycin, phenylalanine, proline, valine, leucine, serine or tyrosine.
Claim 9
Dependent Claim
18 words
A prolinal derivative of the general formula I according to claim 5 for use as a therapeutical agent.
Claim 10
Dependent Claim
20 words
A prolinal derivative of the general formula I according to claim 5 for use in the treatment of memory disorders.
References Cited (Backward Citations)
No citation records indexed.
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