EP0153113A2
Expired / Lapsed
EP
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Thermospray ion sampling device
Assignee: Thermo Finnigan LLC
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Filing: 1985-02-08
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Granted: —
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Expires: 2005-02-08
Abstract
Abstract The performance of a thermospray ion source for liquid chromatograph/mass spectrometers is improved dramatically by providing a voltage gradient across the thermospray jet stream to increase the efficiency of transferring ions of all masses from the thermospray jet stream to the mass spectrometer, and in particular the intensity of high mass ions relative to low mass ions.
Inventors
- 👤 William H. Mcfadden
- 👤 Michael G. Tucker
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-05 19:04
CPC Classifications
H; H01; H01J; H01J49/00; H01J49/02; H01J49/04; H01J49/0468; H01J49/049; H01J49/0431; H01J49/0445; H01J49/06; H01J49/067
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
76 words
A thermospray ion sampling device comprising means (21, 22) to direct a high velocity jet stream into a chamber (23) in a chamber block (32) having an orifice (27) therein through which sample ions from the jet stream leave the chamber (23), characterised by means (31, 28 or 32, 28) to provide a voltage gradient across the jet stream adjacent the orifice (27) thereby to direct sample ions from the jet stream to the orifice (27).
Claim 2
Dependent Claim
76 words
A thermospray ion sampling device comprising means (21, 22) to direct a high velocity jet stream into a chamber (23) in a chamber block (32) having an orifice (27) therein through which sample ions from the jet stream leave the chamber (23), characterised by means (31, 28 or 32, 28) to provide a voltage gradient across the jet stream adjacent the orifice (27) thereby to direct sample ions from the jet stream to the orifice (27).
Claim 3
Dependent Claim
54 words
A device as claimed in Claim 1, characterised in that said means to provide a voltage gradient comprises a repeller electrode (31) mounted in the chamber block (32) opposite the orifice (27) and electrically isolated from the chamber block (32), the voltage gradient being established between the repeller electrode (31) and-the chamber block (32).
Claim 4
Dependent Claim
54 words
A device as claimed in Claim 1, characterised in that said means to provide a voltage gradient comprises a conductive cone member (28) providing the orifice (27) and mounted on the chamber block (32) electrically isolated therefrom, the voltage gradient being established between the cone member ( 28 ) and the chamber block (32).
Claim 5
Dependent Claim
54 words
In a thermospray ion source of the kind which forms a jet stream, including sample ions, which expands to cause ions to flow through an orifice disposed adjacent to said stream to analyzing means, the improvement comprising means forming a voltage gradient across said stream toward said orifice to impel ions to said orifice.
Claim 6
Dependent Claim
54 words
In a thermospray ion source of the kind which forms a jet stream, including sample ions, which expands to cause ions to flow through an orifice disposed adjacent to said stream to analyzing means, the improvement comprising means forming a voltage gradient across said stream toward said orifice to impel ions to said orifice.
Claim 7
Dependent Claim
34 words
5, A thermospray ion source as in Claim 4, in which said means includes a repeller electrode disposed opposite said orifice, whereby voltage may be applied to the repeller to form the voltage gradient.
Claim 8
Dependent Claim
35 words
A thermospray ion source as in Claim 1, in which said orifice is formed in a conductive member insulated from the source whereby voltage may be applied to the cone to form the voltage gradient.
Claim 9
Dependent Claim
21 words
A thermospray ion source as in Claim 1, including means for independently ionizing said jet stream prior to passing said orifice.
Claim 10
Independent Claim
44 words
The method of improving the efficiency of a thermospray ion source of the type which projects a jet stream past a sampling orifice, which comprises the step of generating a voltage gradient across said stream adjacent said orifice to impel ions into said orifice,
Claim 11
Independent Claim
44 words
The method of improving the efficiency of a thermospray ion source of the type which projects a jet stream past a sampling orifice, which comprises the step of generating a voltage gradient across said stream adjacent said orifice to impel ions into said orifice,
Claim 12
Dependent Claim
21 words
The method as in Claim 5, where the voltage gradient is increased as the analyzing apparatus analyzes ions of higher masses.
References Cited (Backward Citations)
No citation records indexed.
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