EP0149551A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Gamma interferon-interleukin-2 synergistic compositions and processes therefor
Assignee: Genentech Inc
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Filing: 1985-01-15
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Granted: —
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Expires: 2005-01-15
Abstract
Abstract Compositions containing therapeutically synergistic mixtures of purified gamma interferon and purified interleukin-2 are provided for treatment of tumor-bearing hosts. Preferably, the gamma interferon and interleukin-2 are obtained from recombinant cell synthesis.
Inventors
- 👤 Michael Angelo Palladino
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-04 17:06
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/19; A61K38/21; A61K38/217; A61P; A61P35/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
11 words
A composition comprising human IFN-y and IL-2 in synergistically effective amounts.
Claim 2
Dependent Claim
11 words
A composition comprising human IFN-y and IL-2 in synergistically effective amounts.
Claim 3
Dependent Claim
14 words
The composition of Claim 1 in admixture with at least one pharmaceutically acceptable excipient.
Claim 4
Dependent Claim
12 words
The composition of Claim 1 or 2 which is prepared in vitro.
Claim 5
Dependent Claim
25 words
The composition of Claim 1 or 2 which is prepared by administering at least portions of human IL-2 and IFN-y separately to a subject mammal.
Claim 6
Dependent Claim
18 words
The composition of Claim 1-4 wherein the human IFN- Y active ingredient is substantially free of interfering impurities.
Claim 7
Dependent Claim
17 words
The composition of Claim 5 wherein the human IL-2 active ingredient is substantially free of interfering impurities.
Claim 8
Dependent Claim
20 words
A process for producing a composition having synergistic biological effect comprising combining synergistically potentiating amounts of human IFN-y and IL-2.
Claim 9
Dependent Claim
20 words
A process for producing a composition having synergistic biological effect comprising combining synergistically potentiating amounts of human IFN-y and IL-2.
Claim 10
Dependent Claim
13 words
The process of Claim 7 wherein said combining is carried out in vitro.
Claim 11
Dependent Claim
13 words
The process of Claim 7 wherein said combining is carried out in vivo.
Claim 12
Dependent Claim
22 words
The use of human IL-2 and IFN- Y for the manufacture of a therapeutic composition containing a synergistic mixture of those substances.
Claim 13
Dependent Claim
22 words
The use of human IL-2 and IFN- Y for the manufacture of a therapeutic composition containing a synergistic mixture of those substances.
References Cited (Backward Citations)
No citation records indexed.
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