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EP0136782A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Chondroitin sulfate/sodium hyaluronate compositions

Assignee: Nestle SA
•
Filing: 1984-08-01
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Granted: —
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Expires: 2004-08-01
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Abstract

Abstract Aqueous composition comprising an aqueous buffer, chondroitin sulfate or a sodium, potassium, magnesium or calcium salt thereof and sodium, potassium, magnesium or calcium hyaluronate; and process for the preparation of such a composition which comprises admixing the individual components. The aqueous composition is particularly useful for use in protecting human or animal cell layers or tissues subject to exposure to trauma.

Inventors

  • 👤 Allison S. Chang
  • 👤 James Edward Boyd
  • 👤 Harold Otto Koch
  • 👤 Richard Michael Johnson

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-05 10:03
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0048; A61P; A61P17/00; A61P43/00

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 24 words
Aqueous composition comprising an aqueous buffer, chondroitin sulfate or a sodium, potassium, magnesium or calcium salt thereof and sodium, potassium, magnesium or calcium hyaluronate.
Claim 2
Dependent Claim 24 words
Aqueous composition comprising an aqueous buffer, chondroitin sulfate or a sodium, potassium, magnesium or calcium salt thereof and sodium, potassium, magnesium or calcium hyaluronate.
Claim 3
Dependent Claim 41 words
Composition according to claim 1 wherein from about 0.1 percent to about 50 percent by weight of the total composition is chondroitin sulfate and from about 0.1 percent to about 50 percent by weight of the total composition is sodium hyaluronate.
Claim 4
Dependent Claim 50 words
Composition according to claim 2 wherein sodium hyaluronate is used as a concentration of from 0.1 g up to about 10 g in 100 mls. of water and chondroitin sulfate is used as a concentration of from about 0.1 g up to about 10 g in 100 mls. of water.
Claim 5
Dependent Claim 34 words
Composition according to claim 1, 2 or 3 wherein about 5.3 percent by weight of the total composition is chondroitin sulfate and about 4.2 percent by weight of the total solution is sodium hyaluronate.
Claim 6
Dependent Claim 41 words
Composition according to claim 1, 2, 3 or 4 wherein the aqueous buffer includes monobasic sodium phosphate, dibasic sodium phosphate and sodium chloride mixed to maintain a pH_of about 7.0 to about 8.0 and an osmolarity of 300 to 350 mOsmol/kg.
Claim 7
Dependent Claim 16 words
Composition according to any of claims 1 to 5, for use as an active therapeutic material.
Claim 8
Dependent Claim 25 words
Composition according to any of claims 1 to 5, for use in protecting human or animal cell layers or tissues subject to exposure to trauma.
Claim 9
Dependent Claim 23 words
Process for the preparation of an aqueous composition according to any of claims 1 to 7 wherein the individual components are mixed together.

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