EP0119861A1
Expired / Lapsed
EP
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Multilayer analytical element for quantitative analysis of bilirubin
Assignee: Fujifilm Holdings Corp
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Filing: 1984-03-19
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Granted: —
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Expires: 2004-03-19
Abstract
Abstract A multilayer analytical element for quantitative analysis of bilirubin in a liquid sample by a diazo method, which comprises a laminated structure consisting essentially of: (1) a porous reagent layer containing an acidic binder and a diazonium salt being reactive to bilirubin to produce azobilirubin; (2) an absorbent layer capable of absorbing an excessive liquid portion; and (3) a liquid-impermeable light-transmissive support.
Inventors
- 👤 Harumi Katsuyama
- 👤 Shigeki Kageyama
- 👤 Shigeru Nagatomo
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-01 17:55
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/72; G01N33/728
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
62 words
A multilayer analytical element for quantitative analysis of bilirubin in a liquid sample by a diazo method, which comprises a laminated structure consisting essentially of: (1) a porous reagent layer containing an acidic binder and a diazonium salt being reactive to bilirubin to produce azobilirubin; (2) an absorbent layer capable of absorbing an excessive liquid portion; and (3) a liquid-impermeable light-transmissive support.
Claim 2
Dependent Claim
62 words
A multilayer analytical element for quantitative analysis of bilirubin in a liquid sample by a diazo method, which comprises a laminated structure consisting essentially of: (1) a porous reagent layer containing an acidic binder and a diazonium salt being reactive to bilirubin to produce azobilirubin; (2) an absorbent layer capable of absorbing an excessive liquid portion; and (3) a liquid-impermeable light-transmissive support.
Claim 3
Dependent Claim
41 words
The analytical element claimed in claim 1, in which said absorbent layer comprises a hyrophilic polymer having a degree of swelling in water at 30 0 C in the range of 1.5 to 30 times as much as the original volume.
Claim 4
Dependent Claim
18 words
The analytical element claimed in claim 1 or 2, in which said absorbent layer contains a basic polymer.
Claim 5
Dependent Claim
59 words
The analytical element claimed in claim 3, in which said basic polymer is: a homopolymer of an unsaturated monomer selected from the group consisting of 2-vinylpyridine, 4-vinylpyridine, N-vinylimidazole, I-vinyl-3-alkyl-2,3-dihydroimidazole, 2-vinyl-l-alkyl-imidazole, (dialkylamino)alkyl acrylate, (dialkylamido)alkyl methacrylate, N-[(di- alkylamlno)alkyl]acrylamide, and N-[(dialkylamino)-alkyl]methacrylamide; a copolymer of said unsaturated monmers; or a copolymer of said unsaturated monomer and other unsaturated monomer than said unsaturated monomer.
Claim 6
Dependent Claim
66 words
The analytical element claimed in claim 1 or 2, in which said acidic binder is: a homopolymer of unsaturated monomer selected from the group consiting of p-styrenesulfonic acid, acrylic acid, methacrylic acid, maleic acid, maleic anhydride, maleic acid monoamide, maleic acid monoester, N-(sulfoalkyl)acrylamide, and N-(sulfoalkyl)methacrylamide; a copolymer of said unsaturated monmers; or a copolymer of said unsaturated monomer and other unsaturated monomer than said unsaturated monomer.13
Claim 7
Dependent Claim
29 words
The analytical element claimed in claim 1 or 2, in which a layer for preventing diffusion of analyte is provided between the porous reagent layer and the absorbent layer.
References Cited (Backward Citations)
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