EP0119737A2
Expired / Lapsed
EP
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Pharmaceutical composition and its production
Assignee: Takeda Pharmaceutical Co Ltd
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Filing: 1984-02-15
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Granted: —
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Expires: 2004-02-15
Abstract
Abstract An aqueous preparation, which comprises an active ingredient, cyclodextrin and a compound of the formula: <CHEM> wherein R is alkyl, X is halogen, n is an integer of 0 to 2 and m is an integer of 1 to 3. The use of the compound as the preservative in the present pharmaceutical does not result in decrease in antimicrobial activity.
Inventors
- 👤 Shin-Ichiro 201-202 Gouchi Hirai
- 👤 Kumiko Jono
- 👤 Hisayoshi Shimizu
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-27 14:45
CPC Classifications
B; B82; B82Y; B82Y5/00; A; A61; A61K; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K47/30; A61K47/36; A61K47/40; A61K47/50; A61K47/69; A61K47/6949; A61K47/6951; A61K9/00; A61K9/0012; A61K9/0014; A61K9/0019; C; C08; C08B; C08B37/00; C08B37/0006; C08B37/0009; C08B37/0012; C08B37/0015
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
39 words
An aqueous preparation which comprises an active ingredient, cyclodextrin and a compound of the formula: wherein R is alkyl, X is halogen, n is an integer of 0 to 2 and m is an integer of 1 to 3.
Claim 2
Dependent Claim
39 words
An aqueous preparation which comprises an active ingredient, cyclodextrin and a compound of the formula: wherein R is alkyl, X is halogen, n is an integer of 0 to 2 and m is an integer of 1 to 3.
Claim 3
Dependent Claim
11 words
A preparation as claimed in Claim 1, wherein X is chlorine.
Claim 4
Dependent Claim
11 words
A preparation as claimed in Claim 1, wherein X is bromine.
Claim 5
Dependent Claim
14 words
A preparation as claimed in Claim 2, wherein the compound is p-chloro-m-xylenol or p-chloro-m-cresol.
Claim 6
Dependent Claim
14 words
A preparation as claimed in Claim 3, wherein the compound is p-bromo-m-cresol or p-bromo-m-xylenol.
Claim 7
Dependent Claim
17 words
A preparation as claimed in Claim 1, wherein the active ingredient is a physiologically active polypeptide drug.
Claim 8
Dependent Claim
19 words
A preparation as claimed in Claim 6 wherein the physiologically active polypeptide drug is (Pyr)Glu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHCH 2 CH 3 .
Claim 9
Dependent Claim
15 words
A preparation as claimed in Claim 6, wherein the physiologically active polypeptide drug is L-pyroglutamyl-L-histidyl-L-prolinamide.tartrate.
Claim 10
Dependent Claim
12 words
A preparation as claimed in Claim 1, wherein the cyclodextrin is a-cyclodextrin.
Claim 11
Dependent Claim
12 words
A preparation as claimed in Claim 1, wherein the cyclodextrin is β-cyclodextrin.
References Cited (Backward Citations)
No citation records indexed.
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