EP0113078A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
DNA complementary to RNA of human leukemia virus
Assignee: Japanese Foundation for Cancer Research
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Filing: 1983-12-06
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Granted: —
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Expires: 2003-12-06
Abstract
Abstract Described is a viral genomic DNA and fragments thereof complementary to genomic RNA of human leukemia virus and a recombinant DNA molecules containing the genomic DNA or fragments thereof. The genomic DNA and fragments thereof and the recombinant DNA molecules are useful for the diagnosis, prevention and therapy of human leukemia.
Inventors
- 👤 Mitsuaki Yoshida
- 👤 Haruo Sugano
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-08 08:34
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/005; C12; C12Q; C12Q1/00; C12Q1/70; C12Q1/701; C12Q1/702; C12N; C12N2740/00; C12N2740/00011; C12N2740/10011; C12N2740/14011; C12N2740/14022
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
16 words
(1) A viral genomic DNA and fragments thereof complementary to genomic RNA of human leukemia virus.
Claim 2
Dependent Claim
28 words
(2) The DNA according to claim 1, wherein the human leukemia virus is an adult T-cell leukemia virus (referred to as ATLV hereinafter) or a virus analogous thereto.
Claim 3
Dependent Claim
36 words
(3) The DNA according to claim 2, wherein the genomic DNA consists of at least 9032 base pairs and has five restriction enzyme sites for PstI, three for HindIII, one for XhoI and two for BamHI.
Claim 4
Dependent Claim
18 words
(4) The DNA according to claim 3 the entire base sequence of which is illustrated in Table 1.
Claim 5
Dependent Claim
20 words
(5) A novel recombinant DNA harboring a viral genomic DNA or fragments thereof complementary to RNA of human leukemia virus.
Claim 6
Dependent Claim
20 words
(6) The recombinant DNA according to claim 5, wherein the human leukemia virus is ATLV or a virus analogous thereto.
Claim 7
Dependent Claim
38 words
(7) The recombinant DNA according to claim 5, wherein the viral generic DNA consists of at least 9032 base pairs and has five restriction enzyme sites for PstI, three for HindIII, one for XhoI and two for BamHI.
Claim 8
Dependent Claim
22 words
(8) The recombinant DNA according to claim 5, wherein the recombinant DNA is constructed of a plasmid DNA derived from Escherichia coli.
Claim 9
Dependent Claim
23 words
(9) The recombinant DNA according to claim 5, wherein the recombinant DNA is constructed of a phage DNA which propagates in Escherichia coli.
Claim 10
Dependent Claim
20 words
(10) The recombinant DNA according to claim 5 which has the cleavage sites for restriction enzymes shown in Fig. 1.
References Cited (Backward Citations)
No citation records indexed.
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