Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
139 words
An arrangement for the removal of one or more fractions out of whole blood, plasma or otner similar body fluids with the help of adsorption on an adsorption column (23, 24) comprising means for the feed in turn of the said fluid to the column and a regenerating fluid, respectively, and means for the removal of said fluids, characterized in that the said means for the removal of the fluids comprise a valve means (33, 34) which is adapted to control the flow from the column (23, 24) in dependence of an analysis carried out by a coarse analysing device (31, 32) to feed said flow either to a second analysing device (38, 46, 47) for the fine analysis of the fluid or back to the source (1) of the same, e.g. a patient, or to a drain (36).
Claim 2
Dependent Claim
139 words
An arrangement for the removal of one or more fractions out of whole blood, plasma or otner similar body fluids with the help of adsorption on an adsorption column (23, 24) comprising means for the feed in turn of the said fluid to the column and a regenerating fluid, respectively, and means for the removal of said fluids, characterized in that the said means for the removal of the fluids comprise a valve means (33, 34) which is adapted to control the flow from the column (23, 24) in dependence of an analysis carried out by a coarse analysing device (31, 32) to feed said flow either to a second analysing device (38, 46, 47) for the fine analysis of the fluid or back to the source (1) of the same, e.g. a patient, or to a drain (36).
Claim 3
Dependent Claim
54 words
An arrangement in accordance with claim , characterized--in that the said analysing device (31, 32) for coarse analysis is constituted of a detector for the monitoring of the degree of dilution of the treated fluid, e.g. a whole blood detector in the treatment of blood or a plasma detector in the treatment of plasma.
Claim 4
Dependent Claim
45 words
An arrangement in accordance with anyone of the preceding claims, characterized by a valve device (21, 22) arranged upstreams of the column which is adapted so that it can convey alternately the treated fluid and regenerat- ting liquid and/or a flushing liquid to the column.
Claim 5
Dependent Claim
83 words
An arrangement in accordance with claim 3, wherein the said regenerating liquid is adapted to lower the pH of the column gradually during a certain period, characterized in that means (51, 52) are adapted so that at the start of the period a rapid lowering is achieved so as to accelerate the starting of the regeneration, whereupon the lowering is adapted so as to occur slowly during the actual regeneration, and preferably to be terminated rapidly during the finish of the said period.
Claim 6
Dependent Claim
22 words
An arrangement in accordance with claim 1, characterized in that the second analysing device is constituted of a pH meter (38, 46).
Claim 7
Dependent Claim
28 words
An arrangement in accordance with claim 1, characterized in that the second analysing device is constituted of a protein deteccor (47) for the monitoring of the separated fraction.
Claim 8
Dependent Claim
42 words
An arrangement in accordance with anyone of claims 5-6, characterized by a further valve device (48) arranged downstream of the second analysing device (46,47) and controlled by the same for the conveying of the separated fraction to a special collecting receiver (37).
Claim 9
Dependent Claim
39 words
An arrangement in accordance with claim 7, characterized in that the said further valve device is adapted so as to.be controlled by two analysing devices (46 and 47) arranged upstream, namely a pH-meter (46) and a protein detector (47).
Claim 10
Dependent Claim
27 words
An arrangement in accordance with anyone of the preceding claims, characterized in that at least two columns (23,24) are connected in parallel for alternate adsorption and regeneration.
Claim 11
Dependent Claim
30 words
An arrangement in accordance with anyone of the preceding claims, characterized in that the column (23,24) contains factor IX bound to agarose for the removal of antibodies against factor IX.
Claim 12
Dependent Claim
31 words
An arrangement in accordance with anyone of claims 1-9, characterized in that the column (23,24) contains protein A for the removal of one or several protein fractions of the IgG type.