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EP0111389A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Substantially pure porcine growth hormone, DNA sequences therefor, and expression vehicles and transfected microorganisms for the production of porcine growth hormone

Assignee: Genentech Inc
•
Filing: 1983-11-04
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Granted: —
•
Expires: 2003-11-04
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Abstract

Abstract The DNA and amino acid sequence of porcine growth hormone are disclosed. The DNA is used to produce substantially pure porcine growth hormone by recombinant DNA technology.

Inventors

  • 👤 John P. Adelman
  • 👤 Peter H. Seeburg

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-24 11:00
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/575; C07K14/61

Claims Analysis

Total Claims: 18
Claim 1
Independent Claim 17 words
Substantially pure porcine growth hormone whose amino acid sequence.is substantially as is shown in Figure 2 hereof.
Claim 2
Dependent Claim 17 words
Substantially pure porcine growth hormone whose amino acid sequence.is substantially as is shown in Figure 2 hereof.
Claim 3
Dependent Claim 15 words
Porcine growth hormone according to Claim 1, as a product of genetically altered cell culture.
Claim 4
Dependent Claim 12 words
Porcine growth hormone according to Claim 1, unaccompanied by associated native glycosylation.
Claim 5
Dependent Claim 18 words
A DNA sequence comprising a sequence encoding porcine growth hormone substantially as is shown in Figure 2 hereof.
Claim 6
Dependent Claim 18 words
A DNA sequence comprising a sequence encoding porcine growth hormone substantially as is shown in Figure 2 hereof.
Claim 7
Dependent Claim 18 words
The DNA sequence according to Claim 4 operably linked with a DNA sequence capable of effecting expression thereof.
Claim 8
Dependent Claim 18 words
An expression vehicle capable, in a transfected cell culture, of expressing a DNA sequence according to Claim 5.
Claim 9
Dependent Claim 11 words
A cell culture transfected with the vehicle according to Claim 6.
Claim 10
Dependent Claim 13 words
A microorganism according to Claim 7, obtained by transfecting an E. coli strain.
Claim 11
Dependent Claim 14 words
A cell culture according to Claim 7, obtained by transfecting a mammalian cell culture.
Claim 12
Dependent Claim 2 words
Plasmid pPGHex-1.
Claim 13
Dependent Claim 2 words
Plasmid pPGHex-1.
Claim 14
Dependent Claim 11 words
A cell culture transfected with the plasmid according to Claim 10.
Claim 15
Dependent Claim 16 words
A culture of cells genetically altered so as to direct the production of porcine growth hormone.
Claim 16
Dependent Claim 16 words
A culture of cells genetically altered so as to direct the production of porcine growth hormone.
Claim 17
Dependent Claim 16 words
A composition of matter comprising porcine growth hormone essentially free of other proteins of porcine origin.
Claim 18
Dependent Claim 16 words
A composition of matter comprising porcine growth hormone essentially free of other proteins of porcine origin.

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