EP0107498A2
Expired / Lapsed
EP
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Synergistic human interferon activity
Assignee: Genentech Inc
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Filing: 1983-10-24
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Granted: —
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Expires: 2003-10-24
Abstract
Abstract A composition comprising (1) human gamma interferon and (2) human alpha interferon or a hybrid thereof or human beta interferon exhibits activities higher than could have been fairly predicted based upon their respective activities when tested alone.
Inventors
- 👤 Christine W. Czarniecki
- 👤 Ernst H. Rinderknecht
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-26 22:04
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/19; A61K38/21; A61K38/217; A61P; A61P43/00
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
29 words
A composition of matter comprising human gamma interferon in synergistic, pharmaceutically pure mixture with a second interferon which is human alpha interferon, a hybrid thereof or human beta interferon.
Claim 2
Dependent Claim
29 words
A composition of matter comprising human gamma interferon in synergistic, pharmaceutically pure mixture with a second interferon which is human alpha interferon, a hybrid thereof or human beta interferon.
Claim 3
Dependent Claim
26 words
The composition according to claim 1 wherein the active interferon constituents are provided in individual purities of greater than 95 percent by weight of total protein.
Claim 4
Dependent Claim
21 words
The composition according to claim 1 or 2 wherein the active interferon constituents are products of genetically altered host cell culture.
Claim 5
Dependent Claim
20 words
The composition according to any one of the preceding claims wherein the active interferon constituents are substantially free of impurities.
Claim 6
Dependent Claim
22 words
The composition according to any one of claims 1 to 3 wherein human gamma interferon is present substantially free of interfering components.
Claim 7
Dependent Claim
18 words
The composition according to any one of the preceding claims wherein the second interferon io human alpha interferon.
Claim 8
Dependent Claim
18 words
The composition according to any one of the preceding claims formulated with a pharmaceutically acceptable diluent or carrier.
Claim 9
Dependent Claim
3 words
Claims for Austria
Claim 10
Dependent Claim
37 words
A process for producing a composition having synergistic biological effect comprising combining pharmaceutically pure, synergistically potentiating amounts of human gamma interferon and a second interferon which is human alpha interferon, a hybrid thereof or human beta interferon.
Claim 11
Dependent Claim
37 words
A process for producing a composition having synergistic biological effect comprising combining pharmaceutically pure, synergistically potentiating amounts of human gamma interferon and a second interferon which is human alpha interferon, a hybrid thereof or human beta interferon.
Claim 12
Dependent Claim
26 words
The process according to claim 1 wherein the active interferon constituents are provided in individual purities of greater than 95 percent by weight of total protein.
Claim 13
Dependent Claim
21 words
The process according to claim 1 or 2 wherein the active interferon constituents are products of genetically altered host cell culture.
Claim 14
Dependent Claim
20 words
The process according to any one of the preceding claims wherein the active interferon constituents are substantially free of impurities.
Claim 15
Dependent Claim
22 words
The process according to any one of claims 1 to 3 wherein human gamma interferon is present substantially free of interfering components.
Claim 16
Dependent Claim
18 words
The process according to any one of the preceding claims wherein the second interferon is human alpha interferon.
Claim 17
Dependent Claim
18 words
The process according to any one of the preceding claims formulated with a pharmaceutically acceptable diluent or carrier.
Claim 18
Dependent Claim
37 words
A process for producing a composition having synergistic biological effect comprising combining pharmaceutically pure, synergistically potentiating amounts of human gamma interferon and a second interferon which is human alpha interferon, a hybrid thereof or human beta interferon.
Claim 19
Dependent Claim
37 words
A process for producing a composition having synergistic biological effect comprising combining pharmaceutically pure, synergistically potentiating amounts of human gamma interferon and a second interferon which is human alpha interferon, a hybrid thereof or human beta interferon.
References Cited (Backward Citations)
No citation records indexed.
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