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EP0103899A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Hollow fiber-type artificial lung
Assignee: Terumo Corp
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Filing: 1983-09-21
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Granted: —
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Expires: 2003-09-21
Abstract
Abstract An artificial lung (11, 111, 250) has an axially extending housing which accommodates a bundle of hollow fibers (17, 116,146) retained within the housing (15,114,251) by a pair of walls (18, 19, 119, 120, 256, 257) provided at the ends of the housing. The housing has blood inlet (27,129,263) and outlet ports (28,132, 268) defining a blood chamber (26, 128, 262) within the housing. Oxygen gas is passed through the hollow fibers (16, 115, 254) and blood is passed through the blood chamber so that a gas exchange may take place through the hollow fiber walls. The artificial lung is provided with a blood reservoir chamber (131, 158) integral with the blood chamber and capable of being communicated with the blood chamber, so that blood which has undergone a gas exchange inside the chamber may be stored within the reservoir. A heat exchanger (269, 298) is disposed at a point preceding, following or intermediate the blood chamber and blood reservoir chamber, which construct a blood circuit.
Inventors
- 👤 Hiromichi Fukasawa
- 👤 Takashi Monzen
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-26 02:43
CPC Classifications
B; B01; B01D; B01D63/00; B01D63/02; A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1621; A61M1/1623; A61M1/1625; A61M1/1629; A61M1/1698; A61M1/36; A61M1/3621; A61M1/3623; A61M1/3643; A61M1/3644; A61M1/3627; B01D2313/00; B01D2313/08
Claims Analysis
Total Claims: 36
Claim 1
Independent Claim
279 words
A hollow fiber-type artificial lung comprising: an axially extended housing; a hollow fiber bundle having a multiplicity of hollow fibers accommodated within and along the axial direction of said housing, said hollow fibers forming blood channels between outer wall surfaces of neighboring ones thereof, and being arranged within said housing in such a manner that neighboring blood channels are brought into substantial communication; first and second walls liquid-tightly supporting said hollow fibers at both end portions thereof within said housing; gas inlet means provided on an outer side of at least one of said first and second walls and communicating with the hollow interior of said hollow fibers; said first and second walls, the inner wall of said housing and the outer wall surfaces of said hollow fibers defining a blood chamber; blood inlet and outlet means communicating with said blood chamber; said blood chamber having a first blood flow passage at a portion adjacent said first wall, said first blood flow passage communicating with said blood inlet means and surrounding said hollow fiber bundle circumferentially at the end portion retained by said first wall, and a second blood flow passage at a portion adjacent said second wall, said second blood flow passage communciating with said blood outlet means and surrounding said hollow fiber bundle circumferentially at the end portion retained by said second wall; a hollow fiber constricting portion for varying the cross sectional area of the blood channels formed between neighboring ones of said hollow fibers; and gas venting means communicating with the interior of said blood chamber, said venting means being situated higher than said blood outlet means when the artificial lung is in use. -
Claim 2
Dependent Claim
279 words
A hollow fiber-type artificial lung comprising: an axially extended housing; a hollow fiber bundle having a multiplicity of hollow fibers accommodated within and along the axial direction of said housing, said hollow fibers forming blood channels between outer wall surfaces of neighboring ones thereof, and being arranged within said housing in such a manner that neighboring blood channels are brought into substantial communication; first and second walls liquid-tightly supporting said hollow fibers at both end portions thereof within said housing; gas inlet means provided on an outer side of at least one of said first and second walls and communicating with the hollow interior of said hollow fibers; said first and second walls, the inner wall of said housing and the outer wall surfaces of said hollow fibers defining a blood chamber; blood inlet and outlet means communicating with said blood chamber; said blood chamber having a first blood flow passage at a portion adjacent said first wall, said first blood flow passage communicating with said blood inlet means and surrounding said hollow fiber bundle circumferentially at the end portion retained by said first wall, and a second blood flow passage at a portion adjacent said second wall, said second blood flow passage communciating with said blood outlet means and surrounding said hollow fiber bundle circumferentially at the end portion retained by said second wall; a hollow fiber constricting portion for varying the cross sectional area of the blood channels formed between neighboring ones of said hollow fibers; and gas venting means communicating with the interior of said blood chamber, said venting means being situated higher than said blood outlet means when the artificial lung is in use. -
Claim 3
Dependent Claim
31 words
The artificial lung according to claim 1, wherein said gas venting means and said blood outlet means are provided at positions substantially symmetrical with respect to the axis of said housing.
Claim 4
Dependent Claim
46 words
The artificial lung according to claim 1, wherein said second wall has a concave portion on a side facing said second blood flow passage, and said gas venting means is provided in a side wall of said housing adjacent the concave portion of said second wall.
Claim 5
Dependent Claim
17 words
The artificial lung according to claim 1, wherein said hollow fibers are made of a microporous membrane.
Claim 6
Dependent Claim
70 words
The artificial lung according to claim 1, wherein the inner surface of said housing in the vicinity of said blood inlet means is flared outwardly relative to the inner surface of the housing at the intermediate portion thereof, thereby forming said first blood flow passage between the outer periphery of said hollow fiber bundle and the inner surface of said housing, said first blood flow passage being annular in shape.
Claim 7
Dependent Claim
69 words
The artificial lung according to claim 1, wherein the inner surface of said housing in the vicinity of said blood outlet means is flared outwardly relative to the inner surface of the housing at the intermediate portion thereof, thereby forming said second blood flow passage between the outer periphery of said hollow fiber'bundle and the inner surface of said housing, said second blood flow passage being annular in shape.
Claim 8
Dependent Claim
65 words
The artificial lung according to claim 5, wherein the flared inner surface of said housing in the vicinity of said blood inlet means is off centered with respect to said hollow fiber bundle so as to increase the distance between said blood inlet means and said hollow fiber bundle, thereby enlarging the flow area of said first blood flow passage facing said blood inlet means.
Claim 9
Dependent Claim
65 words
The artificial lung according to claim 6, wherein the flared inner surface of said housing in the vicinity of said blood outlet means is off centered with respect to said hollow fiber bundle so as to increase the distance between said blood outlet means and said hollow fiber bundle, thereby enlarging the flow area of said second blood flow passage facing said blood outlet means.
Claim 10
Dependent Claim
28 words
The artificial lung according to claim 6, wherein said gas venting means comprises a gas venting port having a detachable filter permeable to gas and impermeable to bacteria.
Claim 11
Dependent Claim
184 words
A hollow fiber-type artificial lung comprising: an axially extended housing; a hollow fiber bundle having a multiplicity of hollow fibers accommodated within and along the axial direction of said housing, said hollow fibers forming blood channels between outer wall surfaces of neighboring ones thereof, and being arranged within said housing in such a manner that neighboring blood channels are brought into substantial communication; first and second walls liquid-tightly supporting said hollow fibers at both end portions thereof within said housing; said first and second walls, the inner wall of said housing and the outer wall surfaces of said hollow fibers defining a blood chamber; blood inlet means provided in a side wall of said housing in the vicinity of said first wall and communicating with said blood chamber; a blood reservoir chamber provided in the vicinity of said second wall and communicating with said blood chamber; blood outlet means communicating with said blood reservoir chamber; and gas inlet means provided on an outer side of at least one of said first and second walls and communicating with the hollow interior of said hollow fibers.
Claim 12
Dependent Claim
184 words
A hollow fiber-type artificial lung comprising: an axially extended housing; a hollow fiber bundle having a multiplicity of hollow fibers accommodated within and along the axial direction of said housing, said hollow fibers forming blood channels between outer wall surfaces of neighboring ones thereof, and being arranged within said housing in such a manner that neighboring blood channels are brought into substantial communication; first and second walls liquid-tightly supporting said hollow fibers at both end portions thereof within said housing; said first and second walls, the inner wall of said housing and the outer wall surfaces of said hollow fibers defining a blood chamber; blood inlet means provided in a side wall of said housing in the vicinity of said first wall and communicating with said blood chamber; a blood reservoir chamber provided in the vicinity of said second wall and communicating with said blood chamber; blood outlet means communicating with said blood reservoir chamber; and gas inlet means provided on an outer side of at least one of said first and second walls and communicating with the hollow interior of said hollow fibers.
Claim 13
Dependent Claim
20 words
The artificial lung according to claim 10, further comprising gas venting means communicating said blood reservoir chamber with the atmosphere.
Claim 14
Dependent Claim
29 words
The artificial lung according to claim 10, wherein said blood reservoir chamber has an outer wall comprising a rigid material, a side surface of said outer wall having graduations.
Claim 15
Dependent Claim
56 words
The artificial lung according to claim 10, wherein said blood reservoir chamber is so adapted that, when blood is introduced from said blood inlet means so as to rise within said blood chamber, the blood will flow downwardly into said blood reservoir chamber from said blood chamber and will be collected within said blood reservoir chamber.
Claim 16
Dependent Claim
61 words
The artificial lung according to claim 10, wherein the inner surface of said housing in the vicinity of said blood inlet means is flared outwardly relative to the inner surface of the housing at the intermediate portion thereof, thereby forming an annular blood flow passage between the outer periphery of said hollow fiber bundle and the inner surface of said housing.
Claim 17
Dependent Claim
64 words
The artificial lung according to claim 14, wherein the flared inner surface of said housing in the vicinity of said blood inlet means is off centered with respect to said hollow fiber bundle so as to increase the distance between said blood inlet means and said hollow fiber bundle, thereby enlarging the flow area of said blood flow passage facing said blood inlet means.
Claim 18
Dependent Claim
59 words
The artificial lung according to claim 10, wherein said housing comprises an inner cylinder defining said blood chamber, and an outer cylinder surrounding a portion of said inner cylinder for defining said blood reservoir chamber between itself and said inner cylinder, said first wall being retained in said inner cylinder, said second wall being retained in said outer cylinder.
Claim 19
Dependent Claim
52 words
The artificial lung according to claim 10, wherein said housing comprises an inner cylinder defining said blood chamber, and an outer cylinder surrounding a portion of said inner cylinder for defining said blood reservoir chamber between itself and said inner cylinder, said first and second walls being retained in said inner cylinder.
Claim 20
Dependent Claim
17 words
The artificial lung according to claim 10, wherein said hollow fibers are made of a microporous membrane.
Claim 21
Dependent Claim
27 words
The artificial lung according to claim 11, wherein said gas venting means comprises a gas venting port having a filter permeable to gas and impermeable to bacteria.
Claim 22
Dependent Claim
207 words
A hollow fiber-type artificial lung comprising: an axially extended housing; a hollow fiber bundle having a multiplicity of hollow fibers accommodated within and along the axial direction of said housing, said hollow fibers forming blood channels between outer wall surfaces of neighboring ones thereof, and being arranged within said housing in such a manner that neighboring blood channels are brought into substantial communication; first and second walls liquid-tightly supporting said hollow fibers at both end portions thereof within said housing; said first and second walls, the inner wall of said housing and the outer wall surfaces of said hollow fibers defining a blood chamber; blood inlet means provided in a side wall of said housing in the vicinity of said first wall and having an opening communicating with said blood chamber; blood outlet means provided in a side wall of said housing in vicinity of said second wall and having an opening communicating with said blood chamber; a heat exchanger provided integral with a blood flow passage, which is formed by said blood chamber, at least at an upstream, downstream or intermediate portion of said blood flow passage; and gas inlet means provided on an outer side of at least one of said first and second walls.
Claim 23
Dependent Claim
207 words
A hollow fiber-type artificial lung comprising: an axially extended housing; a hollow fiber bundle having a multiplicity of hollow fibers accommodated within and along the axial direction of said housing, said hollow fibers forming blood channels between outer wall surfaces of neighboring ones thereof, and being arranged within said housing in such a manner that neighboring blood channels are brought into substantial communication; first and second walls liquid-tightly supporting said hollow fibers at both end portions thereof within said housing; said first and second walls, the inner wall of said housing and the outer wall surfaces of said hollow fibers defining a blood chamber; blood inlet means provided in a side wall of said housing in the vicinity of said first wall and having an opening communicating with said blood chamber; blood outlet means provided in a side wall of said housing in vicinity of said second wall and having an opening communicating with said blood chamber; a heat exchanger provided integral with a blood flow passage, which is formed by said blood chamber, at least at an upstream, downstream or intermediate portion of said blood flow passage; and gas inlet means provided on an outer side of at least one of said first and second walls.
Claim 24
Dependent Claim
24 words
the artificial lung according to claim 20, further comprising a blood reservoir provided on the side of said blood outlet means of said housing.
Claim 25
Dependent Claim
22 words
The artificial lung according to claim 20, wherein said heat exchanger is provided in said blood chamber on said blood outlet means.
Claim 26
Dependent Claim
17 words
The artificial lung according to claim 21, wherein said heat exchanger is provided within said blood reservoir.
Claim 27
Dependent Claim
28 words
The artificial lung according to claim 20, wherein said housing has a blood inlet port, said heat exchanger being provided on the side of said blood inlet port.
Claim 28
Dependent Claim
58 words
The artificial lung according to claim 20, wherein said heat exchanger comprises a bundle of a multiplicity of slender tubes supported at both ends, which ends are open, the hollow interiors of said tubes defining blood flow passages, said heat exchanger being so adapted that a heat transfer medium may be passed along the periphery of said tubes.
Claim 29
Dependent Claim
27 words
The artificial lung according.to claim 20, wherein said heat exchanger comprises a tubular body through the hollow interior of which a heat transfer medium may be passed.
Claim 30
Dependent Claim
19 words
The artificial lung according to claim 20, wherein said blood reservoir has a gas vent communicating with the atmosphere.
Claim 31
Dependent Claim
23 words
The artificial lung according to claim 20, wherein said blood reservoir has an outer wall comprising a rigid material, siad wall having graduations.
Claim 32
Dependent Claim
16 words
The artificial lung according to claim 20, wherein said hollow fibers are made of microporous membrane.
Claim 33
Dependent Claim
66 words
The artificial lung according to claim 20, wherein said housing comprises an inner cylinder accommodating said hollow fibers, and an outer cylinder surrounding a portion of said inner cylinder for defining said blood reservoir between itself and said inner cylinder, said first wall supporting said hollow fibers being retained in said inner cylinder, said second wall supporting said hollow fibers being retained in said outer cylinder.
Claim 34
Dependent Claim
55 words
The artificial lung according to claim 20, wherein said housing comprises an inner cylinder accommodating said hollow fibers, and an outer cylinder surrounding a portion of said inner cylinder for defining said blood reservoir between itself and said inner cylinder, said first and second walls supporting said hollow fibers being retained in said inner cylinder.
Claim 35
Dependent Claim
57 words
The artificial lung according to claim 21, wherein the inner surface of said housing at a portion communicating with said blood inlet means is flared outwardly relative to the intermediate portion of said housing, thereby forming an annular blood flow passage between the outer periphery of said hollow fiber bundle and the inner surface of said housing.
Claim 36
Dependent Claim
64 words
The artificial lung according to claim 31, wherein the flared inner surface of said housing in the vicinity of said blood inlet means is off centered with respect to said hollow fiber bundle so as to increase the distance between said blood inlet port and said hollow fiber bundle, thereby enlarging the flow area of said blood flow passage facing said blood inlet means.
References Cited (Backward Citations)
No citation records indexed.
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