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EP0092438A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Method and apparatus for measuring cardiac output

Assignee: Purdue Research Foundation
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Filing: 1983-04-20
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Granted: —
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Expires: 2003-04-20
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Abstract

Abstract Cardiac output is measured utilizing an indicator, such as saline, which alters blood resistivity, and an electrically calibrated conductivity cell positioned at the tip of a catheter. The catheter with the tetrapolar conductivity cell at the top is inserted into a blood vessel for current injection to develop a potential which is proportional to blood resistivity for inscribing the dilution curve occurring due to injection of the indicator, which curve is utilized to determine blood flow or cardiac output.

Inventors

  • 👤 Leslie A. Geddes
  • 👤 David S. Grubbs

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-25 23:26
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/14542; A61B5/02; A61B5/026; A61B5/0275; A61B5/1468; A61B5/1473; A61B5/68; A61B5/6846; A61B5/6847; A61B5/6852

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 65 words
An apparatus for enabling measurement of cardiac output by determination of blood resistivity, said apparatus comprising: detector means; positioning means for adapting said detector to be positioned in the flow path of blood; and electrical means including calibration means, said electrical means being connected with said detector means for generating an output that is proportional to the resistivity of the blood in said flow path.
Claim 2
Independent Claim 65 words
An apparatus for enabling measurement of cardiac output by determination of blood resistivity, said apparatus comprising: detector means; positioning means for adapting said detector to be positioned in the flow path of blood; and electrical means including calibration means, said electrical means being connected with said detector means for generating an output that is proportional to the resistivity of the blood in said flow path.
Claim 3
Dependent Claim 24 words
The apparatus of Claim 1 wherein said apparatus includes indicating means for receiving said output from said electrical means and indicating said blood resistivity.
Claim 4
Dependent Claim 14 words
The apparatus of Claim 2 wherein said indicating means includes a digital readout device.
Claim 5
Dependent Claim 26 words
The apparatus of Claim 2 wherein said indicating means includes means for enabling inscribing of the dilution curve indicative of sense changes of said blood resistivity.
Claim 6
Dependent Claim 13 words
The apparatus of Claim 1 wherein said detector means is a conductivity cell.
Claim 7
Dependent Claim 15 words
60 The apparatus of Claim 5 wherein said conductivity cell is a tetrapolar conductivity cell.
Claim 8
Dependent Claim 38 words
7 o The apparatus of Claim 6 wherein said tetrapolar conductivity cell includes a pair of exciting electrodes and a pair of output electrodes, and wherein said electrical means includes a constant-current source connected with said exciting electrodes.
Claim 9
Dependent Claim 21 words
The apparatus of Claim 5 wherein said positioning means includes a catheter having said conductivity cell positioned at the tip thereof.
Claim 10
Dependent Claim 26 words
9 o The apparatus of Claim 8 wherein said conductivity cell is a tetrapolar conductivity cell having four electrodes arranged along said tip of said catheter.
Claim 11
Dependent Claim 39 words
The apparatus of Claim 8 wherein said catheter is adapted for insertion in a blood vessel, has an inflatable balloon therein, and at least a first lumen for inflation of said balloon and a second lumen for injecting indicator.
Claim 12
Independent Claim 133 words
An apparatus for enabling measurement of cardiac output by determination of blood resisitivity, said apparatus comprising: a tetrapolar conductivity cell having four electrodes: a catheter having said conductivity cell positioned on the tip thereof, said catheter being adapted for insertion into a body so that said conductivity cell is in the flow path of blood in said body: a constant-current source connected with two of said electrodes of said conductivity cell; first amplifying means connected with the other two of said electrodes of said conductivity cell; indicating means connected with said first amplifying means for indicating resistivity; isolation means connected with said first amplifying means; and second amplifying means connected with said isolation means and providing an isolated analog output of blood resistivity for enabling inscribing of the dilution curve of blood resistivity.
Claim 13
Independent Claim 133 words
An apparatus for enabling measurement of cardiac output by determination of blood resisitivity, said apparatus comprising: a tetrapolar conductivity cell having four electrodes: a catheter having said conductivity cell positioned on the tip thereof, said catheter being adapted for insertion into a body so that said conductivity cell is in the flow path of blood in said body: a constant-current source connected with two of said electrodes of said conductivity cell; first amplifying means connected with the other two of said electrodes of said conductivity cell; indicating means connected with said first amplifying means for indicating resistivity; isolation means connected with said first amplifying means; and second amplifying means connected with said isolation means and providing an isolated analog output of blood resistivity for enabling inscribing of the dilution curve of blood resistivity.
Claim 14
Dependent Claim 56 words
The apparatus of Claim 11 wherein said electrodes of said conductivity cell are spaced with respect to one another along the end of the tip of said catheter, and wherein said outer two of said electrodes are connected with said constant-current source and the inner two of said electrodes are connected with said first amplifying means.

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