EP0086070A2
Expired / Lapsed
EP
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Skin treatment composition
Assignee: Unilever NV
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Filing: 1983-01-31
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Granted: —
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Expires: 2003-01-31
Abstract
Abstract A cosmetically acceptable composition for topical application to human skin comprises from 0.1 to 20% by weight of a substituted 2-hyroxyoctanoic acid or 2-ketooctanoic acid or a mixture thereof, together with an amount of a special neutralising agent sufficient to adjust the pH of the composition to a value of from 3 to 7. The special neutralising agent is one having a cation whose ionic radius is at least 100 pm.
Inventors
- 👤 Martin Douglas Barratt
- 👤 Paul Anthony Bowser
- 👤 James Alan Durrant
- 👤 Dieno George
- 👤 Keith John Hall
- 👤 John Christopher Hill
- 👤 Michael Richard Lowry
- 👤 Colin Prottey
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-05 07:11
CPC Classifications
A; A61; A61Q; A61Q19/00; A61Q19/007; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/36; A61K8/365
Claims Analysis
Total Claims: 36
Claim 1
Independent Claim
73 words
A cosmetically acceptable aqueous composition for topical application to human skin, which composition comprises: (i) from 0.1 to 20% by weight of a substituted octanoic acid chosen from 2-hydroxyoctanoic acid, 2-ketooctanoic acid or a mixture thereof; and (ii) an amount of neutralising agent sufficient to adjust the pH of the composition to a value of from 3 to 7, the neutralising agent having a cation whose ionic radius is at least 100 pm.
Claim 2
Dependent Claim
73 words
A cosmetically acceptable aqueous composition for topical application to human skin, which composition comprises: (i) from 0.1 to 20% by weight of a substituted octanoic acid chosen from 2-hydroxyoctanoic acid, 2-ketooctanoic acid or a mixture thereof; and (ii) an amount of neutralising agent sufficient to adjust the pH of the composition to a value of from 3 to 7, the neutralising agent having a cation whose ionic radius is at least 100 pm.
Claim 3
Dependent Claim
22 words
A composition according to claim 1, in which the substituted octanoic acid forms from 1 to 10% by weight of the composition.
Claim 4
Dependent Claim
26 words
A composition according to claim 1 or 2, in which the neutralising agent is one having a cation whose ionic radius is at least 130 pm.
Claim 5
Dependent Claim
26 words
A composition according to claim 1 or 2, in which the neutralising agent is one having a cation whose ionic radius is at least 150 pm.
Claim 6
Dependent Claim
26 words
A composition according to claim 1 or 2, in which the neutralising agent is one having a cation whose ionic radius is at least 200 pm.
Claim 7
Dependent Claim
15 words
A composition according to any preceding claim, in which the neutralising agent is an alkanolamine.
Claim 8
Dependent Claim
22 words
A composition according to claim 6, in which the alkanolamine is chosen from a mono-, di- or tri-alkanolamine or a mixture thereof.
Claim 9
Dependent Claim
14 words
A composition according to claim 6 or 7, in which the alkanolamine is triethanolamine.
Claim 10
Dependent Claim
14 words
A composition according to claim 6 or 7, in which the alkanolamine is diisopropylamine.
Claim 11
Dependent Claim
24 words
A composition according to any preceding claim, in which the pH of the composition is adjusted to a value of from 3 to 5.
Claim 12
Dependent Claim
24 words
A composition according to any preceding claim, in which the pH of the composition is adjusted to a value of from 3.8 to 4.5.
Claim 13
Dependent Claim
17 words
A composition according to any preceding claim, which comprises from 5 to 95% by weight of water.
Claim 14
Dependent Claim
17 words
A composition according to any preceding claim, further comprising a C 2 to C 4 alkyl lactate.
Claim 15
Dependent Claim
27 words
A composition according to claim 13, in which the alkyl lactate is chosen from ethyl lactate, n-propyl lactate, iso-propyl lactate, n-butyl lactate, iso-butyl lactate and mixtures thereof.
Claim 16
Dependent Claim
22 words
A composition according to claim 13 or 14, in which the lactate forms from 0.1 to 50% by weight of the composition.
Claim 17
Dependent Claim
24 words
A composition according to any of claims 13,14 or 15, in which the lactate forms from 1 to 25% by weight of the composition.
Claim 18
Dependent Claim
22 words
A composition according to any preceding claim, further comprising a C 3 to C 6 2-hydroxyalkanoic acid, 2-ketoalkanoic acid or mixtures thereof.
Claim 19
Dependent Claim
19 words
A composition according to claim 17, in which the C 3 to C 6 2-hydroxyalkanoic acid is 2-hydroxypropionic acid.
Claim 20
Dependent Claim
36 words
A composition according to claim 17 or 18, in which the C 3 to C 6 2-hydroxyalkanoic acid or C 3 to C 8 2-ketoalkanoic acid forms from 0.1 to 20% by weight of the composition.
Claim 21
Dependent Claim
36 words
A composition according to claim 17,18 or 19, in which the C 3 to C 6 2-hydroxyalkanoic acid or C 3 to C 8 2-ketoalkanoic acid forms from 1 to 10% by weight of the composition.
Claim 22
Dependent Claim
31 words
A composition according to any preceding claim, further comprising a plasticisation potentiator as herein defined which is capable of increasing the cloud point temperature of polyoxyethylene(8)nonylphenyl ether by at least 2°C.
Claim 23
Dependent Claim
29 words
A composition according to claim 21, in which the plasticisation potentiator is one which is capable of increasing the cloud point temperature of polyoxyethylene(8)nonylphenyl ether by at least 10°C.
Claim 24
Dependent Claim
29 words
A composition according to claim 21, in which the plasticisation potentiator is one which is capable of increasing the cloud point temperature of polyoxyethylene(8)nonylphenyl ether by at least 13°C.
Claim 25
Dependent Claim
22 words
A composition according to claim 21,22 or 23, in which the plasticisation potentiator is chosen from methanol, ethanol, propane-I-ol and mixtures thereof.
Claim 26
Dependent Claim
22 words
A composition according to claim 21,22 or 23, in which the plasticisation potentiator is chosen from propane-l,2-diol, butane-l,4-diol, dipropane-l,2-diol and mixtures thereof.
Claim 27
Dependent Claim
22 words
A composition according to claim 21,22 or 23, in which the plasticisation potentiator is chosen from n-methyl-2-pyrrolidone, 2-pyrrolidone and a mixture thereof.
Claim 28
Dependent Claim
56 words
A cosmetically acceptable aqueous composition for topical application to human skin, which comprises: (i) from 0.1 to 20% by weight of 2-hydroxyoctanoic acid; (ii) from 0.1 to 50% by weight of ethyl lactate; and (iii) an amount of an alkanolamine sufficient to adjust the pH of the composition to a value of from 3.8 to 4.5.
Claim 29
Dependent Claim
56 words
A cosmetically acceptable aqueous composition for topical application to human skin, which comprises: (i) from 0.1 to 20% by weight of 2-hydroxyoctanoic acid; (ii) from 0.1 to 50% by weight of ethyl lactate; and (iii) an amount of an alkanolamine sufficient to adjust the pH of the composition to a value of from 3.8 to 4.5.
Claim 30
Dependent Claim
56 words
A cosmetically acceptable aqueous composition for topical application to human skin, which comprises: (i) from 0.1 to 20% by weight of 2-hydroxyoctanoic acid; (ii) from 0.1 to 20% by weight of 2-hydroxypropionic acid; and (iii) an amount of an alkanolamine sufficient to adjust the pH of the composition to a value of from 3.8 to 4.5.
Claim 31
Dependent Claim
56 words
A cosmetically acceptable aqueous composition for topical application to human skin, which comprises: (i) from 0.1 to 20% by weight of 2-hydroxyoctanoic acid; (ii) from 0.1 to 20% by weight of 2-hydroxypropionic acid; and (iii) an amount of an alkanolamine sufficient to adjust the pH of the composition to a value of from 3.8 to 4.5.
Claim 32
Dependent Claim
68 words
A cosmetically acceptable aqueous composition for topical application to human skin, which composition comprises: (i) from 0.1 to 20% by weight of 2-hydroxyoctanoic acid; (ii) from 0.1 to 20% by weight of 2-hydroxypropionic acid; (iii) from 0.1 to 50% by weight of ethyl lactate; and (iv) and an amount of an alkanolamine sufficient to adjust the pH of the composition to a value of from 3.8 to 4.5.
Claim 33
Dependent Claim
68 words
A cosmetically acceptable aqueous composition for topical application to human skin, which composition comprises: (i) from 0.1 to 20% by weight of 2-hydroxyoctanoic acid; (ii) from 0.1 to 20% by weight of 2-hydroxypropionic acid; (iii) from 0.1 to 50% by weight of ethyl lactate; and (iv) and an amount of an alkanolamine sufficient to adjust the pH of the composition to a value of from 3.8 to 4.5.
Claim 34
Dependent Claim
89 words
A process for preparing a composition according to any preceding claim, which comprises the steps of: (i) dispersing in water a substituted octanoic acid chosen from 2-hydroxyoctanoic acid, 2-ketooctanoic acid or a mixture thereof; (ii) adjusting the pH of the dispersion to a value of from 3 to 7 with a neutralising agent having a cation whose ionic radius is at least 100 pm, to provide a composition comprising from 0.1 to 20% by weight of the substituted octanoic acid; and (iii) subsequently packaging the composition in a container.
Claim 35
Independent Claim
28 words
A method for the treatment of acne which comprises applying topically to acneic skin an effective amount of a composition according to any of claims 1 to 29.
Claim 36
Dependent Claim
18 words
The use of a composition according to any of claims 1 to 29 in the treatment of acne.
References Cited (Backward Citations)
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