EP0079781A2
Expired / Lapsed
EP
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Ultrafiltering hybrid artificial organ
Assignee: Individual
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Filing: 1982-11-12
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Granted: —
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Expires: 2002-11-12
Abstract
Abstract An artificial hybrid organ or gland is formed from two serially-interconnected chamber (12)(14), the first of which (12) comprises an ultrafiltration chamber which forms an ultrafiltrate from the blood stream applied to it and the second of which (14) comprises a cell exchange chamber which, though immunologically isolated by microporous membranes (16)(18), receives both the bloodstream and the ultrafiltrate and which rapidly exchanges selected constituents with both before they recombine, in order to provide a corrected physiological response to constituents in the blood. Additionally, an optional excretory duct (104) may be employed to channel a portion of the treated ultrafiltrate away from the bloodstream.
Inventors
- 👤 Theodore E. Spielberg
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-07 21:57
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/34; A61M1/3472; A61F; A61F2/00; A61F2/02; A61F2/022; A61M1/3475; A61M1/3486; A61M1/3489; A61M1/36; A61M1/3687; A61M1/3689
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
100 words
An ultrafiltering hybrid artificial organ or gland, said organ or gland providing a differential response to blood constituents, characterized in that it includes an ultrafiltration chamber (12) for receiving blood from a source (29) and for forming both a blood fraction and an ultrafiltrate therefrom, a cell exchange chamber (14) serially connected to said ultrafiltration chamber for receiving both said blood fraction and said ultrafiltrate and configured to enclose a cellular exchange medium (50) for exchanging selected constituents with both the blood fraction and the ultrafiltrate, and means (52) for returning the treated ultrafiltrate and blood fraction to said source.
Claim 2
Dependent Claim
100 words
An ultrafiltering hybrid artificial organ or gland, said organ or gland providing a differential response to blood constituents, characterized in that it includes an ultrafiltration chamber (12) for receiving blood from a source (29) and for forming both a blood fraction and an ultrafiltrate therefrom, a cell exchange chamber (14) serially connected to said ultrafiltration chamber for receiving both said blood fraction and said ultrafiltrate and configured to enclose a cellular exchange medium (50) for exchanging selected constituents with both the blood fraction and the ultrafiltrate, and means (52) for returning the treated ultrafiltrate and blood fraction to said source.
Claim 3
Dependent Claim
40 words
An ultrafiltering hybrid artificial organ or gland according to claim 1, characterized in that the cell exchange chamber (14) includes a microporous membrane transfer means (16)(18) for transferring the selected constituents via the membrane for carrying out the said exchange.
Claim 4
Dependent Claim
28 words
An ultrafiltering hybrid artificial organ or gland according to claim 1, characterised in that it includes means (52) for directly intermixing said treated ultrafiltrate and said blood fraction.
Claim 5
Dependent Claim
66 words
An ultrafiltering hybrid artificial organ or gland according to claim 1, characterised in that there is provided a first cell-free microporous membrane-enclosed channel (22)(24) for ultrafiltration of blood therethrough, and a second microporous membrane-enclosed channel (16) for the passage of treated ultrafiltrate therethrough, a portion of each second channel (16) being positioned for contact with said cellular exchange medium (50) within said cell exchange chamber (14).
Claim 6
Dependent Claim
67 words
An ultrafiltering hybrid artificial organ or gland according to claim 1, characterized in that in operation the exchange chamber (1 1 1) receives said ultrafiltrate for direct contact with said cellular exchange medium (50) and in that there is provided a first microporous membrane-enclosed channel (18) for the passage of blood therethrough for the exchange of constitutents with the medium and the ultrafiltrate via the said membrane.
Claim 7
Dependent Claim
37 words
An ultrafiltering hybrid artificial organ or gland according to claim 1, characterized in that means (9 0 ) (92)(94,96) is provided for altering the ratio of ultrafiltrate to blood fraction applied to said cell exchange chamber (14).
Claim 8
Dependent Claim
50 words
An ultrafiltering hybrid artificial organ or gland according to claim 6, characterized in that said means for altering the ratio includes a conduit (90) for shunting a portion of the blood from said source (29) around said ultrafiltration chamber (12) prior to its application to said cell exchange chamber (14).
Claim 9
Dependent Claim
42 words
An ultrafiltering hybrid artificial organ or gland according to claim 6, characterized in that said means for altering the ratio includes a conduit (92) for shunting a portion of theblood fraction from said ultrafiltration chamber (12) around said cell exchange chamber (14).
Claim 10
Dependent Claim
41 words
An ultrafiltering hybrid artificial organ or gland according to claim 6, characterized in that said means for altering the ratio includes a conduit (94) and a valve (96) for shunting a portion of the ultrafiltrate around said cell exchange chamber (14).
Claim 11
Dependent Claim
32 words
An ultrafiltering hybrid artificial organ according to claim 1, characterized in that there is provided an excretory duct (104) to drain a portion of the treated ultrafiltrate away from the blood stream.
Claim 12
Dependent Claim
32 words
An ultrafiltering hybrid artificial organ according to claim 6, characterized in that there is provided an excretory conduit (104) to drain a portion of the treated ultrafiltrate away from the blood stream.
References Cited (Backward Citations)
No citation records indexed.
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