EP0076136A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Ophthalmic solutions
Assignee: Alcon Vision LLC
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Filing: 1982-09-27
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Granted: —
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Expires: 2002-09-27
Abstract
Abstract This invention relates to the quaternary ammonium salt, α-4-[1-tris (2-hydroxyethyl) ammonium chloride-2-butenyl] poly [1-dimethyl ammonium chloride-2-butenyl]-w-tris (2-hydroxyethyl) ammonium chloride, providing aqueous disinfecting solutions for contact lenses as well as a preservative for ocular solutions including contact lens treating solutions.
Inventors
- 👤 Raymond Lloyd Stark
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-28 22:41
CPC Classifications
A; A61; A61L; A61L12/00; A61L12/08; A61L12/14; A61L12/143; A61L12/145; A61K; A61K31/00; A61K31/74; A61K31/785; A61K9/00; A61K9/0012; A61K9/0048; A61P; A61P27/00; A61P27/02; A61P31/00; A61P31/04; Y; Y02; Y02A; Y02A50/00; Y02A50/30
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
24 words
An aqueous ophthalmic solution comprising: from 0.00001 to 3.0 percent by weight/volume of α-4-[1- tris(2-hydroxyethyl) ammonium chloride-2-buteny17 poly[1-dimethyl ammonium chloride-2-buteny]-w- tris (2-hydroxyethyl) ammonium chloride.
Claim 2
Dependent Claim
24 words
An aqueous ophthalmic solution comprising: from 0.00001 to 3.0 percent by weight/volume of α-4-[1- tris(2-hydroxyethyl) ammonium chloride-2-buteny17 poly[1-dimethyl ammonium chloride-2-buteny]-w- tris (2-hydroxyethyl) ammonium chloride.
Claim 3
Dependent Claim
39 words
An ophthalmic solution as claimed in claim 1 wherein the α-4-[-tris(2-hydroxyethyl) ammonium chloride-2-butenyl7 poly[-dimethyl ammonium chloride-2-butenyl]-w- tris (2-hydroxyethyl) ammonium chloride has a molecular weight sufficiently large to substantially preclude absorption, adsorption or physical binding onto a soft contact lens.
Claim 4
Dependent Claim
34 words
An ophthalmic solution as claimed in claim 1 or claim 2 wherein the α-4-[1-tris(2-hydroxyethyl) ammonium chloride-2-butenyl7 poly[1-dimethyl ammonium chloride-2-butenyl]-w- tris (2-hydroxyethyl) ammonium chloride has a molecular weight in the range from 1200 to 3100.
Claim 5
Dependent Claim
27 words
An ophthalmic solution as claimed in any one of the preceding claims further comprising an antimicrobial agent which is thimerosal, benzalkonium chloride, chlorhexidine, or a mixture thereof.
Claim 6
Dependent Claim
19 words
An ophthalmic solution as claimed in claim 4 comprising from 0.001% by weight/volume to 0.005% by weight/ volume thimerosal.
Claim 7
Dependent Claim
23 words
An ophthalmic solution as claimed in any one of the preceding claims further comprising from 0.01% to 0.2% by weight/volume of polyvinyl alcohol.
Claim 8
Dependent Claim
20 words
An ophthalmic solution as claimed in any one of the preceding claims further comprising 0.2% by weight/ volume of polyvinylpyrrolidone.
Claim 9
Dependent Claim
35 words
An ophthalmic solution as claimed in any one of the preceding claims further comprising disodium edetate, sodium chloride and a buffer, the disinfecting agent having a pH in the range of from 5.0 to 8.5.
Claim 10
Dependent Claim
28 words
A composition for preserving ophthalmic solutions comprising water; and from 0.00001 to 3.0 percent by weight/volume of α-4-[1-tris (2-hydroxyethyl) ammonium chloride-2-butenyl7 poly[1-dimethyl ammonium chloride-2-buteny]-w- tris (2-hydroxyethyl) ammonium chloride.
Claim 11
Dependent Claim
28 words
A composition for preserving ophthalmic solutions comprising water; and from 0.00001 to 3.0 percent by weight/volume of α-4-[1-tris (2-hydroxyethyl) ammonium chloride-2-butenyl7 poly[1-dimethyl ammonium chloride-2-buteny]-w- tris (2-hydroxyethyl) ammonium chloride.
Claim 12
Dependent Claim
30 words
A composition as claimed in claim 9 wherein the α-4-[1-tris (2-hydroxyethyl) ammonium chloride-2-buteny] poly [1-dimethyl ammonium chloride-2-buteny]-w-tris(2-hydroxyethyl) ammonium chloride comprises from 0.0001 to 0.005 percent by weight/volume of the composition.
Claim 13
Dependent Claim
39 words
A composition as claimed in claim 9 or claim 10 wherein the α-4-[-tris (2-hydroxyethyl) ammonium chloride-2-buteny] poly[1-dimethyl ammonium chloride-2-butenyl-w-tris(2-hydroxyethyl) ammonium chloride has a molecular weight sufficiently large to substantially preclude absorption or physical binding onto a soft contact lens.
Claim 14
Dependent Claim
34 words
A composition as claimed in any one of claims 9 to 11 wherein the α-4-[1-tris (21hydroxyethyl) ammonium chloride-2-buteny] poly[-dimethyl ammonium chloride-2-butenyl-w-tris(2-hydroxyethyl) ammonium chloride has a molecular weight in the range from 1200 to 3100.
Claim 15
Dependent Claim
31 words
A composition for disinfecting contact lenses for the human eye comprising water; and from 0.00001 to 3.0 percent by weight/volume of α-4-[1-tris (2-hydroxyethyl) ammonium chloride-2-butenyl7 poly[-dimethyl ammonium chloride-2-butenyl]-w-tris (2-hydroxyethyl) ammonium chloride.
Claim 16
Dependent Claim
31 words
A composition for disinfecting contact lenses for the human eye comprising water; and from 0.00001 to 3.0 percent by weight/volume of α-4-[1-tris (2-hydroxyethyl) ammonium chloride-2-butenyl7 poly[-dimethyl ammonium chloride-2-butenyl]-w-tris (2-hydroxyethyl) ammonium chloride.
Claim 17
Dependent Claim
38 words
A composition for disinfecting contact lenses for the human eye as claimed in claim 13 wherein the α-4-[1-tris (2-hydroxyethyl) ammonium chloride-2-butenyl7 poly[1-dimethyl ammonium chloride-2-buteny]-w-tris (2-hydroxyethyl) ammonium chloride comprises from 0.001 to 0.01 percent by weight/volume of the composition.
Claim 18
Dependent Claim
41 words
A composition as claimed in claim 13 or claim 14 wherein said α-4-[1-tris (2-hydroxyethyl) ammonium chloride-2-buteny] poly[1-dimethyl ammonium chloride-2-butenyl-w-tris (2-hydroxyethyl) ammonium chloride has a molecular weight sufficiently large to substantially preclude adsorption, absorption or physical binding onto a soft contact lens.
Claim 19
Dependent Claim
35 words
A composition as claimed in any one of claims 13 to 15 wherein the α-4-[-tris (2-hydroxyethyl) ammonium chloride-2-buteny] poly[1-dimethyl ammonium chloride-2-butenyl-w-tris (2-hydroxyethyl) ammonium chloride has a molecular weight in the range from 1200 to 3100.
Claim 20
Dependent Claim
27 words
A composition as claimed in any one of claims 13 to 16 further comprising an antimicrobial agent which is thimerosal, benzalkonium chloride, chlorhexidine, or a mixture thereof.
Claim 21
Dependent Claim
18 words
A composition as claimed in any one of claims 13 to 17 further comprising 0.2% by weight/volume polyvinylpyrrolidone.
Claim 22
Dependent Claim
25 words
A composition as claimed in any one of claims 13 to 18 further comprising from 0,01% by weight/volume to 0.2% by weight/volume of polyvinyl alcohol,
Claim 23
Dependent Claim
18 words
A composition as claimed in claim 17 comprising from 0.001%. by weight/volume to 0.005% by weight/volume of thimoseral.
Claim 24
Dependent Claim
34 words
A composition as claimed in any one of claims 13 to 20 further comprising disodium edetate, sodium chloride, and a buffer, the composition having a pH in the range of from 5.0 to 8.5.
Claim 25
Independent Claim
27 words
A method of disinfecting a contact lens comprising placing a contact lens into an aqueous ophthalmic solution as claimed in any one of claims 1 to 8.
References Cited (Backward Citations)
No citation records indexed.
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