Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
31 words
An antigen preparation for use in the reduction or prevention of dental caries comprising antigen C, said preparation being substantially free from any heart cross reactive antigens derivable from Streptococcus mutans.
Claim 2
Dependent Claim
31 words
An antigen preparation for use in the reduction or prevention of dental caries comprising antigen C, said preparation being substantially free from any heart cross reactive antigens derivable from Streptococcus mutans.
Claim 3
Dependent Claim
17 words
An antigen preparation according to claim 1 derived from a strain of Streptococcus mutans genetic group I.
Claim 4
Dependent Claim
16 words
An antigen preparation according to claim 2 derived from a strain of Streptococcus mutans serotype c.
Claim 5
Dependent Claim
18 words
An antigen preparation according to any one of claims 1 to 3 comprising antigen C and antigen A.
Claim 6
Dependent Claim
49 words
A pharmaceutical preparation for use in the reduction or prevention of dental caries comprising an active component in conjunction with a pharmaceutically acceptable diluent or carrier characterised in that the active component is either an antigen preparation according to any one of claims 1 to 4 or antibodies thereto.
Claim 7
Dependent Claim
16 words
A pharmaceutical preparation according to claim 5 in a form suitable for injection or oral administration.
Claim 8
Dependent Claim
27 words
A pharmaceutical preparation according to claim 5 in a form suitable for topical application to the mouth, especially in the form of a toothpaste or a mouthwash.
Claim 9
Dependent Claim
84 words
L. A process for producing an antigen preparation according to any one of claims 1 to 4 comprising growing bacteria of the species Streptococcus mutans in a suitable culture medium, removing at least the cell walls from the resulting culture to leave a protein solution and separating the required antigen preparation from said protein solution characterised in that the antigen preparation is separated from the protein solution by a method of separation including the step of affinity chromatography on immobilised antibody to antigen C.
Claim 10
Dependent Claim
82 words
A process for producing an antigen preparation according to claim 4 comprising growing bacteria of the species Streptococcus mutans in a suitable culture medium, removing at least the cell walls from the resulting culture to leave a protein solution and separating the required antigen preparation from said protein solution characterised in that the antigen preparation is separated from the protein solution by a method of separation including the step of affinity chromatography on immobilised antibody to both antigen C and antigen A.
Claim 11
Dependent Claim
35 words
A process according to either claim 8 or claim 9 characterised in that the bacteria are grown at a dilution rate of between 0.01 and 0.1 hr - 1 , especially about 0.05 hr -1.