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EP0045194A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Oral hygiene compositions comprising Sulfonated poly (arylene ether sulfone) polymers as dental plaque barriers

Assignee: Johnson and Johnson Hospital Services Inc
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Filing: 1981-07-24
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Granted: —
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Expires: 2001-07-24
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Abstract

Abstract Compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated poly(arylene ether sulfone) polymers and the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable vehicle, and a periodic application thereof to teeth.

Inventors

  • 👤 Carl J. Buck
  • 👤 Tibor Sipos
  • 👤 James D. Vidra

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-03 21:37
CPC Classifications
C; C08; C08L; C08L81/00; C08L81/06; A; A61; A61K; A61K8/00; A61K8/02; A61K8/04; A61K8/042; A61K8/18; A61K8/72; A61K8/84; A61K8/86; A61K8/90; A61Q; A61Q11/00; C08G; C08G65/00; C08G65/34; C08G65/48; C08G75/00; C08G75/20; C08G75/23; C08L71/00

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 207 words
An oral hygiene composition comprising an effective amount for preventing attachment of dental plaque to teeth of a sulfonated poly(arylene ether sulfone) polymer having repeating units selected from the group consisting of structure (A), and structure (B), wherein Ar 1 and Ar 2 are each selected from provided further that Ar 2 also can comprise one or more a spacing units selected from -Ar 4 -SO 2 -Ar 4 - and Ar 4 -SO 2 -Ar 4 -SO 2 -Ar 4 -, each Ar 4 .in said spacing units being separately selected from Ar 3 is selected from Ar4 and wherein Y is selected from lower alkylene having 1-5 carbon atoms, lower alkylidine having 2-5 carbon atoms, 0, 5, and 50 2 ; subscript c being an integer selected from 0, 1, and 2, the average quotient obtained by dividing the sum of the c's within each of repeating units (A) and (B) by the number of aromatic groups in said repeating unit being at least about 0.2; and M is selected from the group consisting of lithium, sodium, potassium, calcium, magnesium, zinc, aluminum, hydrogen, ammonium, and substituted ammonium ions derived from pharmaceutically acceptable organic amines, in a pharmaceutically acceptable oral hygiene vehicle compatible with said polymer.
Claim 2
Dependent Claim 207 words
An oral hygiene composition comprising an effective amount for preventing attachment of dental plaque to teeth of a sulfonated poly(arylene ether sulfone) polymer having repeating units selected from the group consisting of structure (A), and structure (B), wherein Ar 1 and Ar 2 are each selected from provided further that Ar 2 also can comprise one or more a spacing units selected from -Ar 4 -SO 2 -Ar 4 - and Ar 4 -SO 2 -Ar 4 -SO 2 -Ar 4 -, each Ar 4 .in said spacing units being separately selected from Ar 3 is selected from Ar4 and wherein Y is selected from lower alkylene having 1-5 carbon atoms, lower alkylidine having 2-5 carbon atoms, 0, 5, and 50 2 ; subscript c being an integer selected from 0, 1, and 2, the average quotient obtained by dividing the sum of the c's within each of repeating units (A) and (B) by the number of aromatic groups in said repeating unit being at least about 0.2; and M is selected from the group consisting of lithium, sodium, potassium, calcium, magnesium, zinc, aluminum, hydrogen, ammonium, and substituted ammonium ions derived from pharmaceutically acceptable organic amines, in a pharmaceutically acceptable oral hygiene vehicle compatible with said polymer.
Claim 3
Dependent Claim 24 words
The composition of Claim 1 wherein M is a metal selected from the group consisting of potassium, lithium, sodium, calcium, magnesium, zinc and aluminum.
Claim 4
Dependent Claim 10 words
The composition of Claim 2 wherein said metal is zinc.
Claim 5
Dependent Claim 22 words
The composition of Claims 1, 2 or 3 wherein said quotient is in the range of from about 0.2 to about 0.5.
Claim 6
Dependent Claim 103 words
The composition of Claims 1 to 4 wherein said sulfonated polymer comprises from about 0.5 to about 10% by weight of the composition, said composition further comprising water, at least about 5% by weight of a humectant selected from the group consisting of glycerol and sorbital, and at least about 16% by weight of a gelling agent selected from the group consisting of the block copolymers of polyoxypropylene and polyoxyethylene wherein the polyoxypropylene component has a molecular weight in the range of from about 3,000 to about 4,000 and the polyoxyethylene comprises between about 25 and about 80 mole percent of said copolymer.
Claim 7
Dependent Claim 24 words
The composition of Claim 5 wherein said sulfonated polymer is present in an amount of from about 2 to about 8 percent by weight.
Claim 8
Dependent Claim 25 words
The composition of Claim 5 or 6 wherein the amount of said gelling agent is from about 16 percent to about 22 percent by weight.
Claim 9
Dependent Claim 17 words
The composition of any one of Claims 1 to 7 which further includes an anticaries fluoride compound.
Claim 10
Dependent Claim 12 words
The composition of Claim 8 wherein said fluoride compound is sodium fluoride.
Claim 11
Dependent Claim 18 words
A composition according to any one of Claims 1 to 9 for use as a plaque prevention agent.

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