EP0020117A2
Expired / Lapsed
EP
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Corticosteroid formulations containing sebacate carrier
Assignee: ER Squibb and Sons LLC
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Filing: 1980-05-23
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Granted: —
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Expires: 2000-05-23
Abstract
Abstract Corticosteroid formulations in the form of creams, lotions or ointments are provided which are used as anti-inflammatory agents, wherein the corticosteroid, such as halcinonide (21-chloro-9-fluoro-11β-hydroxy-16a,17-[(1-methylethylidene)-bis(oxy)]pregn-4-ene-3,20-dione) is dissolved in a sebacate carrier, such as dibutyl sebacate.
Inventors
- 👤 John A. Hill
- 👤 Yu-Chang J. Wang
- 👤 Thomas M. Wong
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-29 15:53
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/56; A61K31/58; A61K31/585; A61K47/00; A61K47/06; A61K47/08; A61K47/14; A61P; A61P29/00
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
23 words
A steroid composition comprising a corticosteroid, and a dialkyl sebacate in an amount of at least about 5% by weight of the composition.
Claim 2
Dependent Claim
23 words
A steroid composition comprising a corticosteroid, and a dialkyl sebacate in an amount of at least about 5% by weight of the composition.
Claim 3
Dependent Claim
31 words
The steroid composition as defined in Claim 1 wherein said sebacate is present in an amount within the range of from about 5 to about 95% by weight of the composition.
Claim 4
Dependent Claim
21 words
The steroid composition as defined in Claim 1 or 2 in the form of an ointment, gel, lotion, cream or solution.
Claim 5
Dependent Claim
62 words
The steroid composition as defined in Claim 3 in the form of a cream or lotion wherein said steroid is present in an amount within the range of from about 0.005 to about 0.6% by weight of the composition, and said sebacate is present in an amount within the range of from about 5 to about 75% by weight of the composition.
Claim 6
Dependent Claim
73 words
The steroid composition as defined in Claim 4 and further including an emulsifier-thickener present in an amount within the range of from about 1 to about 14% by weight of the composition, a preservative present in an amount within, the range of from about 0.05/ to about 50% by weight of the composition, and water present in an amount within the range of from 30 to about 90% by weight of the composition.
Claim 7
Dependent Claim
63 words
The composition as defined in Claim 3 in the form of a lotion wherein said steroid is all-in-solution, said steroid being present in an amount within the range of from about 0.005 to about 0.6% by weight of the composition, and said sebacate being present in an amount within the range of from about 5 to about 75% by weight of the composition.
Claim 8
Dependent Claim
126 words
The steroid composition as defined in Claim 6 further including an emulsifier-thickener present in an amount within the range of from about 5 to about 14% by weight of the composition, a preservative present in an amount within the range of from about 0.05% to about 50% by weight of the composition, and water present in an amount within the range of from about 50 to about 90% by weight of the composition, and optionally including an anti-oxidant present in an amount within the range of from about 0.005 to about 0.1% by weight of the composition, and further optionally including an anti-whitening agent or anti-foaming agent present in an amount within the range of from about 0.2 to about 3% by weight of the composition.
Claim 9
Dependent Claim
61 words
The steroid composition.as defined in Claim 3 in the form of an ointment or gel wherein said steroid is present in an amount within the range of from about 0.001 to about 2% by weight of the composition, and said sebacate is present in an amount within the range of from about 5 to about 75% by weight of the composition.
Claim 10
Dependent Claim
32 words
The steroid composition as defined in Claim 8 further including an oleaginous material present in an amount within the range of from about 25 to about 95% by weight of the composition.
Claim 11
Dependent Claim
14 words
The steroid composition as defined in Claim 9 further including one or more antioxidants.
Claim 12
Dependent Claim
15 words
The steroid composition as defined in any preceding claim wherein said sebacate is dibutyl sebacate.
Claim 13
Dependent Claim
19 words
The steroid composition as defined in any one of claims 1 to 10 wherein said sebacate is diisppropyl sebacate.
Claim 14
Dependent Claim
17 words
The steroid composition as defined in any preceding claim wherein said steroid is halcinonide or triamcinolone acetonide.
References Cited (Backward Citations)
No citation records indexed.
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