EP0017512A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Polymeric materials, process for preparing them and shaped articles and contact lenses formed from them
Assignee: Kelvin Lenses Ltd
•
Filing: 1980-04-09
•
Granted: —
•
Expires: 2000-04-09
Abstract
Abstract Polymeric materials suitable for bio-medical applications, particularly in making contact lenses, are derived by reaction of the following monomers in the given proportions: (1) 20 to 40 mole % of a polymerisable amide which is an unsubstituted or substituted amide of a carboxylic acid containing olefinic unsaturation. (2) 25 to 55 mole % of an N-vinyl lactam, (3) 5 to 20 mole % of a polymerisable ester which is an ester of a carboxylic acid containing olefinic unsaturation. (4) 1 to 10 mole % of a polymerisable carboxylic acid containing olefinic unsaturation, (5) 3 to 10 mole % of a polymerisable hydrophobic vinyl monomer, the amounts of the monomers (1) to (5) totalling 100 mole % and the copolymer being crosslinked with a crosslinking agent. The polymeric materials of the invention may be machined to form contact lenses and subsequently hydrated to form a hydrogel which is suitable for use as an extended wear contact lens.
Inventors
- 👤 Brian John Tighe
- 👤 Howard James Gee
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-25 17:30
CPC Classifications
G; G02; G02B; G02B1/00; G02B1/04; G02B1/041; G02B1/043; C; C08; C08F; C08F220/00; C08F220/02; C08F220/52; C08F220/54; C08F226/00; C08F226/06
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
115 words
A polymeric material suitable for use in biomedical applications comprising units derived from: (1) 20 to 40 mole % of a polymerisable amide which is an unsubstituted or substituted amide of a carboxylic acid containing olefinic unsaturation, (2) 25 to 55 mole % of an N-vinyl lactam, (3) 5 to 20 mole % of a polymerisable ester which is an ester of a carboxylic acid containing olefinic unsaturation, (4) 1 to 10 mole % of a polymerisable carboxylic acid containing olefinic unsaturation, (5) 3 to 10 mole % of a polymerisable hydrophobic vinyl monomer, the amounts of the monomers (1) to (5) totalling 100 mole %, and the copolymer being crosslinked with a crosslinking agent.
Claim 2
Dependent Claim
115 words
A polymeric material suitable for use in biomedical applications comprising units derived from: (1) 20 to 40 mole % of a polymerisable amide which is an unsubstituted or substituted amide of a carboxylic acid containing olefinic unsaturation, (2) 25 to 55 mole % of an N-vinyl lactam, (3) 5 to 20 mole % of a polymerisable ester which is an ester of a carboxylic acid containing olefinic unsaturation, (4) 1 to 10 mole % of a polymerisable carboxylic acid containing olefinic unsaturation, (5) 3 to 10 mole % of a polymerisable hydrophobic vinyl monomer, the amounts of the monomers (1) to (5) totalling 100 mole %, and the copolymer being crosslinked with a crosslinking agent.
Claim 3
Dependent Claim
18 words
A polymeric material according to claim 1 wherein component (1) is an amide of acrylic or methacrylic acid.
Claim 4
Dependent Claim
25 words
A polymeric material according to claim 2 wherein component (1) is acrylamide, methacrylamide or diacetone acrylamide or a mixture of two or all of these.
Claim 5
Dependent Claim
16 words
A polymeric material according to any one of the preceding claims wherein component (2) is N-vinylpyrrolid-2-one.
Claim 6
Dependent Claim
23 words
A polymeric material according to any one of the preceding claims wherein component (3) is a hydroxy substituted-ester of acrylic or methacrylic acid.
Claim 7
Dependent Claim
15 words
A polymeric material according to claim.5 wherein component (3) is hydroxy-propyl acrylate or hydroxyethyl methacrylate.
Claim 8
Dependent Claim
23 words
A polymeric material according to any one of the preceding claims containing units derived from 1 to 3 mole % of component (4).
Claim 9
Dependent Claim
19 words
A polymeric material according to any one of the preceding claims wherein component (4) is acrylic or methacrylic acid.
Claim 10
Dependent Claim
23 words
A polymeric material according to any one of the preceding claims containing units derived from 5 to 10 mole % of component (5).
Claim 11
Dependent Claim
27 words
A polymeric material according to any one of the preceding claims wherein component (5) is styrene, an ester of acrylic or methacrylic acid or a mixture thereof.
Claim 12
Dependent Claim
30 words
A polymeric material according to any one of the preceding claims crosslinked with up to 5 weight % of a crosslinking agent based on the total weight of the monomers.
Claim 13
Dependent Claim
26 words
A polymeric material according to claim 11 crosslinked with up to 1 weight % of a crosslinked agent based on the total weight of the monomers.
Claim 14
Dependent Claim
27 words
A polymeric material according to any one of the preceding claims which is crosslinked to the extent of one crosslink to every 10 to 200 polymer units.
Claim 15
Dependent Claim
47 words
A polymeric material according to any one of the preceding claims wherein the crosslinking agent is ethylene glycol dimethacrylate, a polyethylene oxide dimethacrylate, divinyl benzene, a diamide of an unsaturated aliphatic carboxylic acid, an anhydride of an aliphatic or aromatic carboxylic acid, a diepoxide or dicumyl peroxide.
Claim 16
Dependent Claim
25 words
A polymeric material according to any one of the preceding claims in the form of a hydrogel containing at least 65% by weight of water.
Claim 17
Dependent Claim
22 words
A shaped article, suitable for producing a contact lens, comprising a polymeric material as claimed in any one of the preceding claims.
Claim 18
Dependent Claim
12 words
A contact lens comprising a polymeric material as claimed in claim 15.
Claim 19
Dependent Claim
135 words
A process for preparing a polymeric material suitable for use in biomedical applications which comprises copolymerising a monomer mixture comprising: (1) 20 to 40 mole % of a polymerisahle amide which is an unsubstituted or substituted amide of a carboxylic acid containing olefinic unsaturation, (2) 25 to 55 mole % of an N-vinyl lactam, (3) 5 to 20 mole % of a pblyinerisable ester which is an ester of a carboxylic acid containing olefinic unsaturation, (4) 1 to 10 mole % of a polymerisable carboxylic acid containing olefinic unsaturation, (5) 3 to 10 mole % of a polymerisable hydrophobic vinyl nionomer, mole the amounts of the monomers (1) to (5) totalling 100 mole %, and either the copolymerisation is carried out in the presence of a crosslinking agent or the resulting copolymer is subsequently crosslinked.
Claim 20
Dependent Claim
135 words
A process for preparing a polymeric material suitable for use in biomedical applications which comprises copolymerising a monomer mixture comprising: (1) 20 to 40 mole % of a polymerisahle amide which is an unsubstituted or substituted amide of a carboxylic acid containing olefinic unsaturation, (2) 25 to 55 mole % of an N-vinyl lactam, (3) 5 to 20 mole % of a pblyinerisable ester which is an ester of a carboxylic acid containing olefinic unsaturation, (4) 1 to 10 mole % of a polymerisable carboxylic acid containing olefinic unsaturation, (5) 3 to 10 mole % of a polymerisable hydrophobic vinyl nionomer, mole the amounts of the monomers (1) to (5) totalling 100 mole %, and either the copolymerisation is carried out in the presence of a crosslinking agent or the resulting copolymer is subsequently crosslinked.
Claim 21
Dependent Claim
26 words
1 9 . A process according to claim 18, wherein the polymeric material is as claimed in any one of claims 2 to 1 3 '.
Claim 22
Dependent Claim
16 words
A process according to claim 18 or 19 wherein the copolymerisation is carried out in bulk.
Claim 23
Dependent Claim
18 words
A process according to claim 20 wherein t-butyl peroctoate or methyl ethyl ketone peroxide is added as initiator.
Claim 24
Dependent Claim
25 words
A process according to any one of claims 18 to 21 wherein a crosslinking agent is present in the monomer mixture prior to the copolymerisation.
Claim 25
Dependent Claim
20 words
A process according to claim 22. wherein the crosslinking agent is ethylene glycol dimethacrylate, polyethylene oxide dimethacrylate or divinyl benzene.
Claim 26
Dependent Claim
20 words
A process according to claim 22 or 23 wherein the copolymerisation is performed in amould to produce a shaped article.
Claim 27
Dependent Claim
43 words
25, A process according to any one of claims 18 to 21 wherein a copolymer is produced in linear form from the monomers (1) to (5) and is compression or injection moulded into a shaped article in the presence of a crosslinking agent.
Claim 28
Dependent Claim
19 words
A process according to claim 24 or 25 wherein the shaped article is cut to form a contact lens.
Claim 29
Dependent Claim
28 words
A process according to any one of claims 18 to 26 wherein the product is immersed in water or an aqueous medium untilequilibrium is reached,to form a hydrogel.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.