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EP0013131A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Pharmaceutical composition in solid dosage form, and process for its production

Assignee: Mundipharma AG
•
Filing: 1979-12-19
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Granted: —
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Expires: 1999-12-19
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Abstract

Abstract A pharmaceutical composition in solid dosage form which comprises a core including a first active ingredient and a film coating, characterised in that the film coating contains a second active ingredient. In a preferred embodiment of the pharmaceutical compositions according to the invention, the core contains an iron source, in particular ferrous glycine sulphate, incorporated in a controlled release matrix, and is coated with a film coating containing a vitamin, for example folic acid. The pharmaceutical composition according to the invention is preferably produced by preparing a tablet core containing an active ingredient, then preparing a film coating solution or suspension containing a second active ingredient, and spraying the solution or suspension onto the core.

Inventors

  • 👤 Alan Rhodes
  • 👤 Stewart Thomas Leslie

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-04 21:20
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2072; A61K9/2086; A61K9/209

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 31 words
A pharmaceutical composition in solid dosage form, which comprises a core including a first active ingredient, and a film coating characterised in that the film coating contains a second active ingredient.
Claim 2
Dependent Claim 31 words
A pharmaceutical composition in solid dosage form, which comprises a core including a first active ingredient, and a film coating characterised in that the film coating contains a second active ingredient.
Claim 3
Dependent Claim 53 words
A composition as claimed in claim 1 characterised in that the two active ingredients have different half ' lives of elimination, the active ingredient which requires incorporation within a controlled release system due to its particular half-life of elimination being so incorporated, and the other active ingredient being incorporated within the film coat.
Claim 4
Dependent Claim 30 words
A composition as claimed in claim 2 characterised in that the controlled release system is a matrix which comprises a higher aliphatic alcohol and a hydrated water soluble hydroxyalkyl cellulose.
Claim 5
Dependent Claim 35 words
A composition as claimed in any of claims 1 to 3, characterised in that the core contains an iron source incorporated in a controlled release matrix, and is coated with a film-coating containing a vitamin.
Claim 6
Dependent Claim 23 words
A composition as claimed in claim 4 charactericed in that the iron source is ferrous glycine sulphate and the vitamin is folic acid.
Claim 7
Dependent Claim 28 words
A composition as claimed in any of claims 1 to 3 characterised in that the core contains a bronchodilator and the coating contains a tranquiliser or a potentiator.
Claim 8
Dependent Claim 26 words
A composition as claimed in any of claims 1 to 3 characterised in that the core contains a stimulant and the coating contains an anti-migraine agent.
Claim 9
Dependent Claim 55 words
A process for the preparation of a pharmaceutical composition as claimed in any of claims 1 to 7 characterised in that a tablet core containing an active ingredient is prepared, a film coating solution or suspension containing a second active ingredient is then prepared and the solution or suspension is sprayed on to the core.
Claim 10
Dependent Claim 26 words
A pharmaceutical composition as claimed in any of claims 1 to 7 characterised in that it is prepared by a process as claimed in claim 8.

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