Process for the preparation of lipidic capsules containing a biologically active compound, products obtained by this process as well as their utilisation

Abstract

Abstract Translated from French Procédé de fabrication de capsules synthétiques en matériaux lipidiques renfermant des matériaux biologiquement actifs. On prépare un mélange de lipides dans un solvant organique et un mélange aqueux du matériau destiné à être encapsulé, on émulsifie le mélange obtenu, on extrait le solvant organique et on met le gel résultant en suspension dans de l'eau. On peut encapsuler diverses sortes de matériaux biologiquement actifs, par exemple des médicaments, des bactéries, des insecticides et analogues. Method for manufacturing synthetic capsules made of lipid materials containing biologically active materials. A mixture of lipids in an organic solvent and an aqueous mixture of the material intended to be encapsulated is prepared, the mixture obtained is emulsified, the organic solvent is extracted and the resulting gel is suspended in water. Various kinds of biologically active materials can be encapsulated, for example drugs, bacteria, insecticides and the like.

Inventors

• 👤 Demetrios P. Papahadjopoulos
• 👤 Francis Charles Szoka, Jr.

Bibliographic Details