CA1088539A
Expired / Lapsed
CA
⏱️ 0.0 years remaining
Process for the preparation of 5-(2-chlorobenzyl)-4,5, 6,7-tetrahydrothieno ¬3,2-c| pyridine
Assignee: Sanofi SA
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Filing: 1978-01-26
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Granted: 1980-10-28
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Expires: 1998-01-26
Abstract
Abstract ABSTRACT OF THE DISCLOSURE A process for the preparation of 5-(2-chlorobenzyl)-4,5,6 7-tetrahydrothien?[3,2-c]pyridine, wherein N-(2-thienylethyl)-N-hydroxymethyl-N-(2-chlorobenzyl) amine obtained from N-(2-thienylethyl)-N-(2-chlorobenzyl)amine and formaldehyde is submitted to cyclization.
Inventors
- 👤 Giuseppe Quadro
Bibliographic Details
Application Number
—
Jurisdiction
CA
Data Source
google_patents
Last Synchronized
2026-11-09 23:13
CPC Classifications
C; C07; C07D; C07D495/00; C07D495/02; C07D495/04; C07D333/00; C07D333/02; C07D333/04; C07D333/06; C07D333/14; C07D333/20; C07D333/24
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
23 words
A process for the preparation of 5-(2-chlorobenxyl) -4,5,6,7-tetrahydrothieno [3,2-c] pyridine, wherein N-(2-thienyl-ethyl)-N-hydroxymethyl-N-(2-chlorobenxyl) amine obtained from N-(2-thienylethyl)-N-(2-chlorobenzyl) amine and formaldehyde is submitted to cyclizatlon.
Claim 2
Dependent Claim
23 words
A process for the preparation of 5-(2-chlorobenxyl) -4,5,6,7-tetrahydrothieno [3,2-c] pyridine, wherein N-(2-thienyl-ethyl)-N-hydroxymethyl-N-(2-chlorobenxyl) amine obtained from N-(2-thienylethyl)-N-(2-chlorobenzyl) amine and formaldehyde is submitted to cyclizatlon.
Claim 3
Dependent Claim
20 words
A process as claimed in claim 1, wherein the cyclization is carried out with anhydrous HCl in an anhydrous solvent.
Claim 4
Dependent Claim
13 words
A process as claimed in claim 2, wherein the solvent used is dimethylformamide.
Claim 5
Dependent Claim
28 words
A process as claimed in claims 1-3, wherein the cyclization is carried out directly on the reaction product of N-(2-thienylethyl)-N-(2-chlorobenzyl) amine with formal-dehyde, extracted from the aqueous phase.
References Cited (Backward Citations)
No citation records indexed.
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